I am a postdoctoral fellow at NIEHS, USA. I am particularly interested in genetics, developmental biology, evo-devo, and specifically in sex determination and gonadal development.
Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis
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Martin Estermann
Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart
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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development
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Monica Tambalo et al.
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad
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Martin Estermann
Reconstructing human early embryogenesis in vitro with pluripotent stem cells
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Martin Estermann
Dissecting Mammalian Spermatogenesis Using Spatial Transcriptomics
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Martin Estermann
Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds
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Martin Estermann
Generating single-sex litters: development of CRISPR-Cas9 genetic tools to produce all-male offspring
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Martin Estermann
A spatially resolved single cell atlas of human gastrulation
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Martin Estermann
Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure
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Martin Estermann
Genetic Developmental Timing Revealed by Inter-Species Transplantations in Fish
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Martin Estermann
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites
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Martin Estermann
SEDB 2020 (Spanish Society of Developmental Biology)
List of preprints seen at the 17th Spanish Society for Developmental Biology Meeting
List by | Irepan Salvador-Martinez et al. |
Society for Developmental Biology 79th Annual Meeting
Preprints at SDB 2020
List by | Irepan Salvador-Martinez, Martin Estermann |
5 months
Martin Estermann
As a developmental geneticist, it still fascinates me that aggregated cells in culture have the capacity to form complex embryonic structures with such resemblance to in utero grown embryos. As a young postdoctoral researcher switching from birds to mammalian embryonic models, I now understand the difficulties of in utero development when studying embryonic development. These in vitro embryonic models will allow us to monitor and study mammalian embryonic development, under the microscope, in real time!. Particularly, as I study gonadal development and sex determination, which occurs around E10.5-E12.5 in mice, I am interested to see if these models can continue their development in vitro past the E8.5 developmental stage. The preprints and articles discussed here are the starting point of a new era for mammalian developmental biologists. I can’t wait to see where the science takes us.