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Martin Estermann

NIEHS

I am a postdoctoral fellow at NIEHS, USA. I am particularly interested in genetics, developmental biology, evo-devo, and specifically in sex determination and gonadal development.

Martin Estermann has added 11 preLight posts

Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis

Irene Mota-Gómez, Juan Antonio Rodríguez, Shannon Dupont, et al.



Selected by Martin Estermann

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

Chloé Mayère, Violaine Regard, Aitana Perea-Gomez, et al.



Selected by Martin Estermann

Reconstructing human early embryogenesis in vitro with pluripotent stem cells

Berna Sozen, Victoria Jorgensen, Meng Zhu, et al.



Selected by Martin Estermann

Dissecting Mammalian Spermatogenesis Using Spatial Transcriptomics

Haiqi Chen, Evan Murray, Anisha Laumas, et al.



Selected by Martin Estermann

Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds

Jason Ioannidis, Gunes Taylor, Debiao Zhao, et al.



Selected by Martin Estermann

Generating single-sex litters: development of CRISPR-Cas9 genetic tools to produce all-male offspring

Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, et al.



Selected by Martin Estermann

A spatially resolved single cell atlas of human gastrulation

Richard C.V. Tyser, Elmir Mahammadov, Shota Nakanoh, et al.



Selected by Martin Estermann

Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

Katrin Mangold, Jan Mašek, Jingyan He, et al.



Selected by Martin Estermann

Genetic Developmental Timing Revealed by Inter-Species Transplantations in Fish

Jana Franziska Fuhrmann, Lorena Buono, Juan Ramón Martinez Morales, et al.



Selected by Martin Estermann

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

Jesse V Veenvliet, Adriano Bolondi, Helene Kretzmer, et al.



Selected by Martin Estermann

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Martin Estermann has commented 1 time

5 months

Martin Estermann

As a developmental geneticist, it still fascinates me that aggregated cells in culture have the capacity to form complex embryonic structures with such resemblance to in utero grown embryos. As a young postdoctoral researcher switching from birds to mammalian embryonic models, I now understand the difficulties of in utero development when studying embryonic development. These in vitro embryonic models will allow us to monitor and study mammalian embryonic development, under the microscope, in real time!. Particularly, as I study gonadal development and sex determination, which occurs around E10.5-E12.5 in mice, I am interested to see if these models can continue their development in vitro past the E8.5 developmental stage. The preprints and articles discussed here are the starting point of a new era for mammalian developmental biologists. I can’t wait to see where the science takes us.

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