Synthetic mammalian signaling circuits for robust cell population control

Yitong Ma, Mark W. Budde, Michaëlle N. Mayalu, et al.

Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.

Discussion

Automated continuous evolution of proteins in vivo

Ziwei Zhong, Brandon G. Wong, Arjun Ravikumar, et al.

Axon-like protrusions promote small cell lung cancer migration and metastasis

Dian Yang, Fangfei Qu, Hongchen Cai, et al.

Discussion

Optogenetic control of Wnt signaling for modeling early embryogenic patterning with human pluripotent stem cells

Nicole A. Repina, Xiaoping Bao, Joshua A. Zimmermann, et al.

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Theodore L. Roth, P. Jonathan Li, Jasper F. Nies, et al.

Discussion

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

AND

Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Discussion

Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacteria via Dynamic RNA Nanotechnology

Mikhail H. Hanewich-Hollatz, Zhewei Chen, Jining Huang, et al.

Disrupting Transcriptional Feedback Yields an Escape-Resistant Antiviral

Sonali Chaturvedi, Marie Wolf, Noam Vardi, et al.