Preprint highlights, selected by the biological community
I am a cell and molecular biologist interested in genome stability and gene regulatory mechanisms.
Enhancer-associated H3K4 methylation safeguards in vitro germline competence
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Sree Rama Chaitanya
Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability
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Sree Rama Chaitanya
FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair
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Sree Rama Chaitanya, Giuseppina D'Alessandro
A developmentally programmed splicing failure attenuates the DNA damage response during mammalian zygotic genome activation
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Sree Rama Chaitanya
Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair
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Giuseppina D'Alessandro, Sree Rama Chaitanya
EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break
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Sree Rama Chaitanya
Association analysis of repetitive elements and R-loop formation across species
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Sree Rama Chaitanya
CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy
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Sree Rama Chaitanya
ARID1A regulates R-loop associated DNA replication stress
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Sree Rama Chaitanya
Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
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Sree Rama Chaitanya
SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism
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Sree Rama Chaitanya
Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA clusters in cancer
Selected by
Sree Rama Chaitanya
4 years
Ram
Great post! Much needed for the ‘new normal’. It’s good to see the facts and stats although most of us knew the downsides of conferences and meetings. I was an MSCA fellow and I was ‘spoiled’ with the lavish funding. I guess as scientists we should be much more critical about our way of life and research, not to mention the dier times we are facing now.