Search results

Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive inter- and intra-enhancer redundancy

A. Hörnblad, K. Langenfeld, S. Bastide, et al.

Selected by 25 March 2020

Clarice Hong

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by 20 March 2020

Georgina Sava

Trophectoderm Potency is Retained Exclusively in Human Naïve Cells

Ge Guo, Giuliano Giuseppe Stirparo, Stanley Strawbridge, et al.

Selected by 01 March 2020

Sergio Menchero

Hedgehog signaling is required for endomesodermal patterning and germ cell development in Nematostella vectensis

Cheng-Yi Chen, Sean A. McKinney, Lacey R. Ellington, et al.

Selected by 25 February 2020

Paul Gerald L. Sanchez and Stefano Vianello

Discussion

Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes

Aditi Kulkarni, Wanqin Yu, Alex Moon, et al.

Selected by 12 December 2019

Yasmin Lau

Discussion

Architectural RNA is required for heterochromatin organization

Jitendra Thakur, He Fang, Trizia Llagas, et al.

Selected by 05 December 2019

Ramona Jühlen

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

Tadamoto Isogai, Kevin M. Dean, Philippe Roudot, et al.

Selected by 15 September 2019

Ankita Jha

A conserved ATG2-GABARAP interaction is critical for phagophore closure

Mihaela Bozic, Luuk van den Bekerom, Beth A. Milne, et al.

Selected by 12 September 2019

Mila Basic

Discussion

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.

Selected by 11 September 2019

Sergio Menchero

The histone chaperone FACT induces cas9 multi-turnover behavior and modifies genome manipulation in human cells

Alan S. Wang, Leo Chen, R. Alex Wu, et al.

Selected by 20 August 2019

Nicola Stevenson

Discussion

Cyp26b1 is required for proper airway epithelial differentiation during lung development

Edward Daniel, Gabrielle I. Sutton, Yadanar Htike, et al.

Selected by 19 August 2019

Julio Sainz de Aja

Arl13b regulates Sonic Hedgehog signaling from outside primary cilia

Eduardo D. Gigante, Megan R. Taylor, Anna A. Ivanova, et al.

Selected by 15 August 2019

Alex Eve