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Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Discussion

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Discussion

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

Alessandro Stirpe, Nora Guidotti, Sarah Northall, et al.

Metabolic scaling has diversified among species, despite an evolutionary constraint within species

Julian E. Beaman, Daniel Ortiz-Barrientos, Keyne Monro, et al.

Discussion

Trophic cooperation promotes bacterial survival of Staphylococcus aureus and Pseudomonas aeruginosa

Laura Camus, Paul Briaud, Sylvère Bastien, et al.

Mitophagy protects beta cells from inflammatory damage in diabetes

Vaibhav Sidarala, Gemma L. Pearson, Vishal S. Parekh, et al.

Female-specific upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity

Jason W. Millington, Chien Chao, Ziwei Sun, et al.

Discussion

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.

A subcellular atlas of Toxoplasma reveals the functional context of the proteome

Konstantin Barylyuk, Ludek Koreny, Huiling Ke, et al.

Evolutionary Changes in Left-Right Visceral Asymmetry in Astyanax Cavefish

Li Ma, Mandy Ng, Janet Shi, et al.

Human Hair Graying is Naturally Reversible and Linked to Stress

Ayelet Rosenberg, Shannon Rausser, Junting Ren, et al.

Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism

Sara M. Nowinski, Ashley Solmonson, Scott F. Rusin, et al.