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Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases

King Faisal Yambire, Lorena Fernandez-Mosquera, Robert Steinfeld, et al.

Thyroid hormone regulates distinct paths to maturation in pigment cell lineages

Lauren Saunders, Abhishek Mishra, Andrew J Aman, et al.

Planar differential growth rates determine the position of folds in complex epithelia

Melda Tozluoğlu, Maria Duda, Natalie J Kirkland, et al.

AND

Buckling of epithelium growing under spherical confinement

Anastasiya Trushko, Ilaria Di Meglio, Aziza Merzouki, et al.

Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells

Arnav Moudgil, Michael N Wilkinson, Xuhua Chen, et al.

SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

AND

SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

AND

2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

Discussion

Minimal membrane interactions conferred by Rheb C-terminal farnesylation are essential for mTORC1 activation

Shawn M Ferguson, Brittany Angarola

Regulation of modulatory cell activity across olfactory structures in Drosophila melanogaster

Xiaonan Zhang, Kaylynn Coates, Andrew Dacks, et al.

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

Discussion

A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart

Hessel Honkoop, Dennis de Bakker, Alla Aharonov, et al.

Variability of bacterial behavior in the mammalian gut captured using a growth-linked single-cell synthetic gene oscillator

David T Riglar, David L Richmond, Laurent Potvin-Trottier, et al.

Discussion

A conserved MFS orchestrates a subset of O-glycosylation to facilitate macrophage dissemination and tissue invasion

Katarina Valoskova, Julia Biebl, Marko Roblek, et al.

MRE11-RAD50-NBS1 activates Fanconi Anemia R-loop suppression at transcription-replication conflicts

Emily Yun-Chia Chang, James P Wells, Shu-Huei Tsai, et al.