Search results

Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.

Selected by 14 April 2020

NYUPeerReview

Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

J. Stone Doggett, Tracey Schultz, Alyssa J. Miller, et al.

Selected by 10 April 2020

Zhang-He Goh

Discussion

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

Elaine Thai, Giulia Costa, Anna Weyrich, et al.

Selected by 23 March 2020

Mariana De Niz

Discussion

drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by 20 March 2020

Georgina Sava

Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses

Chris J. de Witte, Jose Espejo Valle-Inclan, Nizar Hami, et al.

Selected by 31 December 2019

Zhang-He Goh

Combining antibiotics with antivirulence compounds is effective and can reverse selection for antibiotic resistance in Pseudomonas aeruginosa

Chiara Rezzoagli, Martina Archetti, Michael Baumgartner, et al.

Selected by 10 December 2019

Zhang-He Goh

Discussion

Hif-1alpha stabilisation is protective against infection in a zebrafish model of comorbidity

Yves Schild, Abdirizak Mohamed, Edward J. Wootton, et al.

Selected by 28 October 2019

Jonny Coates

Discussion

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

Selected by 17 September 2019

Joanna Cross

Discussion

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

Jasper Wouters, Zeynep Kalender-Atak, Liesbeth Minnoye, et al.

Selected by 13 September 2019

Hannah Brunsdon

Discussion

TGFβ restricts T cell function and bacterial control within the tuberculous granuloma

Benjamin H Gern, Kristin N Adams, Courtney R Plumlee, et al.

Selected by 26 July 2019

Kasturi MAHADIK

Discussion

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Fernando Medeiros Filho, Ana Paula Barbosa do Nascimento, Marcelo Trindade dos Santos, et al.

Selected by 19 July 2019

Euan McDonnell

Discussion

Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Discussion