Sick Bats Stay Home Alone: Social distancing during the acute phase response in Egyptian fruit bats (Rousettus aegyptiacus)
Selected by
11 December 2020
Baheerathan Murugavel
Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
Selected by
13 November 2020
Sree Rama Chaitanya
Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors
Selected by
31 October 2020
Zhang-He Goh
The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors
Selected by
21 October 2020
Kristina Kuhbandner
human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
Selected by
10 September 2020
Osvaldo Contreras, Nicolas Collao
Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity
AND
Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity
Selected by
07 August 2020
Zhang-He Goh
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
31 July 2020
Yen-Chung Chen
Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
Selected by
25 July 2020
Josie Gibson, Zhang-He Goh
Surface area-to-volume ratio, not cellular rigidity, determines red blood cell traversal through small capillaries
Selected by
20 July 2020
Mariana De Niz
A systematic examination of preprint platforms for use in the medical and biomedical sciences setting
Selected by
18 July 2020
Sejal Davla
Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports
AND
Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia
Selected by
13 July 2020
Zhang-He Goh
Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model
Selected by
01 July 2020
Zhang-He Goh