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Generative modeling of single-cell population time series for inferring cell differentiation landscapes

Grace H.T. Yeo, Sachit D. Saksena, David K. Gifford

Selected by 06 November 2020

Yen-Chung Chen

Bioinformatics

Parental genome unification is highly erroneous in mammalian embryos

Tommaso Cavazza, Antonio Z Politi, Patrick Aldag, et al.

Selected by 14 September 2020

Madhuja Samaddar

Cell Biology

A spatially resolved single cell atlas of human gastrulation

Richard C.V. Tyser, Elmir Mahammadov, Shota Nakanoh, et al.

Selected by 10 September 2020

Martin Estermann

Developmental Biology

Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle

Jerome Avellaneda, Clement Rodier, Fabrice Daian, et al.

Selected by 04 September 2020

Andrea Irazoki

Cell Biology

Frizzled-dependent Planar Cell Polarity without Wnt Ligands

Joyce J.S. Yu, Aude Maugarny-Calès, Stéphane Pelletier, et al.

AND

Wnt ligands are not required for planar cell polarity in the Drosophila wing or notum

Ben Ewen-Campen, Typhaine Comyn, Eric Vogt, et al.

Selected by 10 August 2020

Helen Zenner

The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos

Selected by 07 August 2020

Sergio Menchero

Molecular Biology

Optoribogenetic control of regulatory RNA molecules

Sebastian Pilsl, Charles Morgan, Moujab Choukeife, et al.

Selected by 05 August 2020

Angika Basant

Molecular Biology

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan Jahnel, Nora Papai, et al.

Selected by 20 July 2020

Alok Javali

Developmental Biology

T cell receptor is required for differentiation but not maintenance of intestinal intraepithelial lymphocytes

Angelina M. Bilate, Mariya London, Tiago B. R. Castro, et al.

Selected by 20 July 2020

Pedro Papotto

Immunology

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

Paolo Armando Gagliardi, Maciej Dobrzyński, Marc-Antoine Jacques, et al.

Selected by 13 July 2020

Mariana De Niz

Cell Biology

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Selected by 13 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Lineage recording reveals dynamics of cerebral organoid regionalization

Zhisong He, Tobias Gerber, Ashley Maynard, et al.

Selected by 10 July 2020

David Wilson, Irepan Salvador-Martinez

Developmental Biology
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