Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly
Selected by
05 June 2021
Joanna Zell
Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones
Selected by
14 April 2021
Utrecht Protein Folding and Assembly
Brain deletion of Serf2 shifts amyloid conformation in a mouse model
Selected by
06 April 2021
Utrecht Protein Folding and Assembly
Structure of an infectious mammalian prion
Selected by
04 March 2021
Jennifer Ann Black
Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations
Selected by
13 February 2020
Tessa Sinnige
HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa
Selected by
27 October 2019
Tessa Sinnige
The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain
Selected by
20 September 2019
Tessa Sinnige
Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning
Selected by
18 July 2019
Suzanne McDermott
Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity
Selected by
11 January 2019
Tessa Sinnige
Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex
Selected by
05 January 2019
Reid Alderson
Structure of a cytochrome-based bacterial nanowire
Selected by
21 December 2018
Amberley Stephens
Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient
Selected by
05 November 2018
Tessa Sinnige