Search results

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

Jemil Ahmed, Tessa C. Fitch, Courtney M. Donnelly, et al.

Selected by 05 June 2021

Joanna Zell

Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones

Unekwu M. Yakubu, Kevin A. Morano

Selected by 14 April 2021

Utrecht Protein Folding and Assembly

Brain deletion of Serf2 shifts amyloid conformation in a mouse model

E. Stroo, L. Janssen, O. Sin, et al.

Selected by 06 April 2021

Utrecht Protein Folding and Assembly

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by 04 March 2021

Jennifer Ann Black

Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations

Ryan R. Cupo, James Shorter

Selected by 13 February 2020

Tessa Sinnige

HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa

Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, et al.

Selected by 27 October 2019

Tessa Sinnige

The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain

Alessia Peduzzo, Sara Linse, Alexander K. Buell

Selected by 20 September 2019

Tessa Sinnige

Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Discussion

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Selected by 11 January 2019

Tessa Sinnige

Discussion

Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

Diego Gauto, Leandro Estrozi, Charles Schwieters, et al.

Selected by 05 January 2019

Reid Alderson

Structure of a cytochrome-based bacterial nanowire

David J Filman, Stephen F Marino, Joy E Ward, et al.

Selected by 21 December 2018

Amberley Stephens

Discussion

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient

Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, et al.

Selected by 05 November 2018

Tessa Sinnige