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Architectural RNA is required for heterochromatin organization

Jitendra Thakur, He Fang, Trizia Llagas, et al.

Selected by 05 December 2019

Ramona Jühlen

Genomics

Epigenetic gene silencing by heterochromatin primes fungal resistance

Sito Torres-Garcia, Pauline N. C. B. Audergon, Manu Shukla, et al.

Selected by 14 November 2019

Miguel V. Almeida

Genetics

The majority of histone acetylation is a consequence of transcription

Benjamin J.E. Martin, Julie Brind’Amour, Kristoffer N. Jensen, et al.

Selected by 18 October 2019

Gabriel Aughey

Molecular Biology

KMT5C displays robust retention and liquid-like behavior in phase separated heterochromatin

Hilmar Strickfaden, Kristal Missiaen, Michael J. Hendzel, et al.

Selected by 30 September 2019

Carmen Adriaens

Biophysics

Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection

Caroline B. Turner, Sean W. Buskirk, Katrina B. Harris, et al.

Selected by 18 September 2019

Defne Surujon

Evolutionary Biology

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

Jasper Wouters, Zeynep Kalender-Atak, Liesbeth Minnoye, et al.

Selected by 13 September 2019

Hannah Brunsdon

Cancer Biology

DropSynth 2.0: high-fidelity multiplexed gene synthesis in emulsions

Angus M. Sidore, Calin Plesa, Joyce A. Samson, et al.

Selected by 23 August 2019

Connor Rosen

Synthetic Biology

Shake-it-off: A simple ultrasonic cryo-EM specimen preparation device

John L. Rubinstein, Hui Guo, Zev A. Ripstein, et al.

Selected by 21 May 2019

David Wright

Biochemistry

Kinesin-6 Klp9 plays motor-dependent and -independent roles in collaboration with Kinesin-5 Cut7 and the microtubule crosslinker Ase1 in fission yeast

Masashi Yukawa, Masaki Okazaki, Yasuhiro Teratani, et al.

Selected by 05 March 2019

Imène Bouhlel

Cell Biology

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Selected by 11 January 2019

Tessa Sinnige

Biophysics

Unlimited genetic switches for cell-type specific manipulation

Jorge Garcia-Marques, Ching-Po Yang, Isabel Espinosa-Medina, et al.

Selected by 09 January 2019

Rafael Almeida

Molecular Biology

Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

Diego Gauto, Leandro Estrozi, Charles Schwieters, et al.

Selected by 05 January 2019

Reid Alderson

Biophysics