From amazing work to I beg to differ - analysis of bioRxiv preprints that received one public comment till September 2019
Selected by
Iratxe Puebla, Jessica Polka
Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models
Selected by
Alexander Ward, Osvaldo Contreras
Open Science Saves Lives: Lessons from the COVID-19 Pandemic
Selected by
Jonny Coates, Dey Lab
Genome-wide maps of enhancer regulation connect risk variants to disease genes
Selected by
Jesus Victorino
Integer topological defects organize stresses driving tissue morphogenesis
Selected by
Yamini Ravichandran, Giulia Paci
Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype
Selected by
Zhang-He Goh
High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells
AND
Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization
Selected by
Kirsty Ferguson
Frizzled-dependent Planar Cell Polarity without Wnt Ligands
AND
Wnt ligands are not required for planar cell polarity in the Drosophila wing or notum
Selected by
Helen Zenner
Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity
AND
Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity
Selected by
Zhang-He Goh
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
Yen-Chung Chen
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
Zhang-He Goh, Josie Gibson
A systematic examination of preprint platforms for use in the medical and biomedical sciences setting
Selected by
Sejal Davla