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Temporal constraints on enhancer usage shape the regulation of limb gene transcription

Raquel Rouco, Antonella Rauseo, Guillaume Sapin, et al.

Selected by 17 April 2024

María Mariner-Faulí

Developmental Biology

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich Sohn

Biochemistry

ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations

Coline Arnould, Vincent Rocher, Aldo S. Bader, et al.

Selected by 17 February 2022

Jennifer Ann Black

Molecular Biology

A “spindle and thread”-mechanism unblocks translation of N-terminally disordered proteins

Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, et al.

Selected by 16 April 2021

Utrecht Protein Folding and Assembly

Biochemistry

MCM complexes are barriers that restrict cohesin-mediated loop extrusion

Bart J. H. Dequeker, Hugo B. Brandão, Matthias J. Scherr, et al.

Selected by 19 November 2020

Jennifer Ann Black

Cell Biology

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.

Selected by 07 September 2020

Jesus Victorino

Genetics

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

Hui Huang, Quan Zhu, Adam Jussila, et al.

Selected by 25 July 2020

Clarice Hong

Genetics

Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomes

Michael Mitter, Catherina Gasser, Zsuzsanna Takacs, et al.

Selected by 09 June 2020

Parna Saha

Molecular Biology

Resolving the 3D landscape of transcription-linked mammalian chromatin folding

Tsung-Han S. Hsieh, Elena Slobodyanyuk, Anders S. Hansen, et al.

Selected by 13 June 2019

Clarice Hong

Genomics

Developmentally regulated Shh expression is robust to TAD perturbations

Iain Williamson, Lauren Kane, Paul S. Devenney, et al.

Selected by 21 May 2019

Jesus Victorino

Genetics

Preformed Chromatin Topology Assists Transcriptional Robustness of Shh during Limb Development

Christina Paliou, Philine Guckelberger, Robert Schöpflin, et al.

Selected by 08 April 2019

Rafael Galupa

Developmental Biology

Functional dissection of tads reveals non-essential and instructive roles in regulating gene expression

Alexandra Despang, Robert Schöpflin, Martin Franke, et al.

Selected by 23 March 2019

Clarice Hong

Genetics
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