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SARS-CoV-2 Variants are Selecting for Spike Protein Mutations that Increase Protein Stability

David Shorthouse, Benjamin. A. Hall

Astrocyte plasticity ensures continued endfoot coverage of cerebral blood vessels and integrity of the blood brain barrier, with plasticity declining with normal aging

William A. Mills III, Shan Jiang, Joelle Martin, et al.

Discussion

Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells

Kyungtae Lim, Walfred Tang, Dawei Sun, et al.

Membrane architecture and adherens junctions contribute to strong Notch pathway activation

Julia Falo-Sanjuan, Sarah J. Bray

STING mediates immune responses in a unicellular choanoflagellate

Arielle Woznica, Ashwani Kumar, Carolyn R. Sturge, et al.

AND

The STING ligand 2’3’-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis

Shally R. Margolis, Peter A. Dietzen, Beth M. Hayes, et al.

Discussion

Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms

Christian Reuter, Fabian Imdahl, Laura Hauf, et al.

YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids

Servando Giraldez, Eleonora Stronati, Ling Huang, et al.

Discussion

The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response

Lei Zhu, Rob W. van der Pluijm, Michal Kucharski, et al.

Discussion

Systematic reconstruction of the cellular trajectories of mammalian embryogenesis

Chengxiang Qiu, Junyue Cao, Tony Li, et al.

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.

Discussion

Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution

Giuliana Rossi, Sonja Giger, Tania Hübscher, et al.

TAZ/TEAD complex regulates TGF-β1-mediated fibrosis in iPSC-derived renal organoids

Xiaoping Yang, Marco Delsante, Parnaz Daneshpajouhnejad, et al.

Discussion