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From amazing work to I beg to differ - analysis of bioRxiv preprints that received one public comment till September 2019

Mario Malički, Joseph Costello, Juan Pablo Alperin, et al.



Selected by Iratxe Puebla, Jessica Polka

Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models

Richard J Mills, Sean J Humphrey, Patrick RJ Fortuna, et al.



Selected by Alexander Ward, Osvaldo Contreras

Open Science Saves Lives: Lessons from the COVID-19 Pandemic

Lonni Besançon, Nathan Peiffer-Smadja, Corentin Segalas, et al.



Selected by Jonny Coates, Dey Lab

Genome-wide maps of enhancer regulation connect risk variants to disease genes

Joseph Nasser, Drew T. Bergman, Charles P. Fulco, et al.



Selected by Jesus Victorino

Integer topological defects organize stresses driving tissue morphogenesis

Pau Guillamat, Carles Blanch-Mercader, Karsten Kruse, et al.



Selected by Yamini Ravichandran, Giulia Paci

Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype

Hafeez S. Haniff, Xiaohui Liu, Laurent Knerr, et al.



Selected by Zhang-He Goh

High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells

Xiaowei Yan, Nico Stuurman, Susana A. Ribeiro, et al.

AND

Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization

Gil Kanfer, Shireen A. Sarraf, Yaakov Maman, et al.



Selected by Kirsty Ferguson

Frizzled-dependent Planar Cell Polarity without Wnt Ligands

Joyce J.S. Yu, Aude Maugarny-Calès, Stéphane Pelletier, et al.

AND

Wnt ligands are not required for planar cell polarity in the Drosophila wing or notum

Ben Ewen-Campen, Typhaine Comyn, Eric Vogt, et al.



Selected by Helen Zenner

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

AND

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.



Selected by Zhang-He Goh

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.



Selected by Yen-Chung Chen

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.



Selected by Zhang-He Goh, Josie Gibson

A systematic examination of preprint platforms for use in the medical and biomedical sciences setting

Jamie J Kirkham, Naomi Penfold, Fiona Murphy, et al.



Selected by Sejal Davla

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