m6A RNA methylation facilitates pre-mRNA 3’-end formation and is essential for viability of Toxoplasma gondii
AND
A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma
Selected by
22 March 2021
Joao Mello-Vieira
From amazing work to I beg to differ - analysis of bioRxiv preprints that received one public comment till September 2019
Selected by
04 March 2021
Iratxe Puebla, Jessica Polka
Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models
Selected by
27 November 2020
Alexander Ward, Osvaldo Contreras
Open Science Saves Lives: Lessons from the COVID-19 Pandemic
Selected by
20 October 2020
Jonny Coates, Dey Lab
Genome-wide maps of enhancer regulation connect risk variants to disease genes
Selected by
30 September 2020
Jesus Victorino
Integer topological defects organize stresses driving tissue morphogenesis
Selected by
27 August 2020
Yamini Ravichandran, Giulia Paci
Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype
Selected by
25 August 2020
Zhang-He Goh
High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells
AND
Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization
Selected by
10 August 2020
Kirsty Ferguson
Frizzled-dependent Planar Cell Polarity without Wnt Ligands
AND
Wnt ligands are not required for planar cell polarity in the Drosophila wing or notum
Selected by
10 August 2020
Helen Zenner
Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity
AND
Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity
Selected by
07 August 2020
Zhang-He Goh
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
31 July 2020
Yen-Chung Chen
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
25 July 2020
Zhang-He Goh, Josie Gibson