Search results

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

Jialin Liu, Rebecca R. Viales, Pierre Khoueiry, et al.

Selected by 11 December 2020

Irepan Salvador-Martinez

Genome-wide maps of enhancer regulation connect risk variants to disease genes

Joseph Nasser, Drew T. Bergman, Charles P. Fulco, et al.

Selected by 30 September 2020

Jesus Victorino

Discussion

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.

Selected by 07 September 2020

Jesus Victorino

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

Hui Huang, Quan Zhu, Adam Jussila, et al.

Selected by 25 July 2020

Clarice Hong

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, et al.

Selected by 30 June 2020

Monica Tambalo

Discussion

LINE elements are a reservoir of regulatory potential in mammalian genomes

Maša Roller, Ericca Stamper, Diego Villar, et al.

Selected by 22 June 2020

Sergio Menchero

Endogenous retroviruses drive species-specific germline transcriptomes in mammals

Akihiko Sakashita, So Maezawa, Kris G. Alavattam, et al.

Selected by 27 May 2020

Petra Kovacikova

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.

Selected by 01 May 2020

Kirsty Ferguson

Discussion

Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

Özgen Deniz, Mamataz Ahmed, Christopher D. Todd, et al.

Selected by 21 April 2020

Jesus Victorino

Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive inter- and intra-enhancer redundancy

A. Hörnblad, K. Langenfeld, S. Bastide, et al.

Selected by 25 March 2020

Clarice Hong

enhancers predominantly regulate gene expression in vivo via transcription initiation

Martin S. C. Larke, Takayuki Nojima, Jelena Telenius, et al.

Selected by 09 December 2019

Clarice Hong

Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications

María Touceda-Suárez, Elizabeth M. Kita, Rafael D. Acemel, et al.

Selected by 14 October 2019

Jesus Victorino