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Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency

Ji-Hoon Lee, Seung W. Ryu, Nicolette A. Ender, et al.

Systematic Engineering of Artificial Metalloenzymes for New-to-Nature Reactions

Tobias Vornholt, Fadri Christoffel, Michela M. Pellizzoni, et al.

Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect splicing

Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice

Yuki Nishimoto, Kazuhiro Ito, Genki Kimura, et al.

Ana1 recruits PLK1 to mother centrioles to promote mitotic PCM assembly and centriole elongation

Ines Alvarez-Rodrigo, Alan Wainman, Jordan W. Raff

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Two microRNAs are sufficient for embryogenesis in C. elegans

Philipp J. Dexheimer, Jingkui Wang, Luisa Cochella

RADX Sustains POT1 Function at Telomeres to Counteract RAD51 Binding, which Triggers Telomere Fragility

Anna-Sophia Briod, Galina Glousker, Joachim Lingner

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.

Regulation of blood cell transdifferentiation by oxygen sensing neurons

Sean Corcoran, Anjeli Mase, Yousuf Hashmi, et al.

Recognition of cellular RNAs by the S9.6 antibody creates pervasive artefacts when imaging RNA:DNA hybrids

John A. Smolka, Lionel A. Sanz, Stella R. Hartono, et al.