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PPARγ mediated enhanced lipid biogenesis fuels mycobacterium tuberculosis growth in hepatocytes

Binayak Sarkar, Jyotsna Singh, Mohit Yadav, et al.

Selected by 14 May 2024

UofA IMB565 et al.

Microbiology

NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis

Hayden T. Pacl, Krishna C. Chinta, Vineel P. Reddy, et al.

Selected by 16 October 2023

Matheus Atella de Oliveira, Marcus Oliveira

Biochemistry

An arginase 2 promoter transgenic illuminates anti-inflammatory signalling in zebrafish

Ffion R. Hammond, Amy Lewis, Holly E. Anderson, et al.

Selected by 10 April 2022

Josie Gibson

Immunometabolic hijacking of immune cells by a Pseudomonas aeruginosa quorum-sensing signal

Arunava Bandyopadhaya, Vijay K Singh, Arijit Chakraborty, et al.

Selected by 14 October 2021

Joao Mello-Vieira

Microbiology

Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control mycobacterium tuberculosis infection in macrophages

Samantha L. Bell, Kayla L. Lopez, Jeffery S. Cox, et al.

Selected by 25 July 2020

Josie Gibson, Zhang-He Goh

Microbiology

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Selected by 25 July 2020

Zhang-He Goh, Josie Gibson

Pharmacology and Toxicology

The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection

Silvia Ferrara, Alice Rossi, Serena Ranucci, et al.

Selected by 25 July 2020

Zhang-He Goh

Pharmacology and Toxicology

A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis

Vivek V. Thacker, Neeraj Dhar, Kunal Sharma, et al.

Selected by 15 July 2020

Snehal Kadam

Microbiology

Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model

Kristina M. Bigelow, Rokeya Tasneen, Yong S. Chang, et al.

Selected by 01 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.

Selected by 18 June 2020

Zhang-He Goh

Pharmacology and Toxicology

Triclosan depletes the membrane potential in Pseudomonas aeruginosa biofilms inhibiting aminoglycoside induced adaptive resistance

Michael M. Maiden, Christopher M. Waters

Selected by 27 April 2020

Amberley Stephens

Microbiology

SIV and mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

Collin R Diedrich, Tara Rutledge, Pauline Maiello, et al.

Selected by 23 April 2020

Louise Fraser

Immunology
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