NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis
Selected by
Matheus Atella de Oliveira, Marcus Oliveira
An arginase 2 promoter transgenic illuminates anti-inflammatory signalling in zebrafish
Selected by
Josie Gibson
Immunometabolic hijacking of immune cells by a Pseudomonas aeruginosa quorum-sensing signal
Selected by
Joao Mello-Vieira
Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control mycobacterium tuberculosis infection in macrophages
Selected by
Josie Gibson, Zhang-He Goh
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
Zhang-He Goh, Josie Gibson
The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection
Selected by
Zhang-He Goh
A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis
Selected by
Snehal Kadam
Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model
Selected by
Zhang-He Goh
Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism
Selected by
Zhang-He Goh
Triclosan depletes the membrane potential in Pseudomonas aeruginosa biofilms inhibiting aminoglycoside induced adaptive resistance
Selected by
Amberley Stephens
SIV and mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis
Selected by
Louise Fraser
Hif-1alpha stabilisation is protective against infection in a zebrafish model of comorbidity
Selected by
Jonny Coates