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Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive inter- and intra-enhancer redundancy

A. Hörnblad, K. Langenfeld, S. Bastide, et al.

Selected by 25 March 2020

Clarice Hong

NINJA: an inducible genetic model for creating neoantigens in vivo

Martina Damo, Brittany Fitzgerald, Yisi Lu, et al.

Selected by 04 March 2020

Deborah Caswell

Cancer Biology

Trophectoderm Potency is Retained Exclusively in Human Naïve Cells

Ge Guo, Giuliano Giuseppe Stirparo, Stanley Strawbridge, et al.

Selected by 01 March 2020

Sergio Menchero

Developmental Biology

regulatory context drives conservation of glycine riboswitch aptamers

Matt Crum, Nikhil Ram-Mohan, Michelle M. Meyer

Selected by 30 October 2019

Defne Surujon

Bioinformatics

Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications

María Touceda-Suárez, Elizabeth M. Kita, Rafael D. Acemel, et al.

Selected by 14 October 2019

Jesus Victorino

Evolutionary Biology

Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation

Masashi Yukawa, Sajjeev Jagannathan, Andrey V. Kartashov, et al.

Selected by 02 August 2019

Jonny Coates

Immunology

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Fernando Medeiros Filho, Ana Paula Barbosa do Nascimento, Marcelo Trindade dos Santos, et al.

Selected by 19 July 2019

Euan McDonnell

Bioinformatics

Resolving the 3D landscape of transcription-linked mammalian chromatin folding

Tsung-Han S. Hsieh, Elena Slobodyanyuk, Anders S. Hansen, et al.

Selected by 13 June 2019

Clarice Hong

Genomics

A conserved regulatory program drives emergence of the lateral plate mesoderm

Karin D. Prummel, Christopher Hess, Susan Nieuwenhuize, et al.

Selected by 06 June 2019

Meng Zhu

Developmental Biology

Developmentally regulated Shh expression is robust to TAD perturbations

Iain Williamson, Lauren Kane, Paul S. Devenney, et al.

Selected by 21 May 2019

Jesus Victorino

Genetics

Preformed Chromatin Topology Assists Transcriptional Robustness of Shh during Limb Development

Christina Paliou, Philine Guckelberger, Robert Schöpflin, et al.

Selected by 08 April 2019

Rafael Galupa

Developmental Biology

Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression

Alexandra Despang, Robert Schöpflin, Martin Franke, et al.

Selected by 23 March 2019

Clarice Hong

Genetics