Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models
Selected by
27 November 2020
Alexander Ward, Osvaldo Contreras

The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors
Selected by
21 October 2020
Kristina Kuhbandner

Intestinal infection results in impaired lung innate immunity to secondary respiratory infection
Selected by
30 September 2020
Josie Gibson

Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice
Selected by
23 September 2020
Zhang-He Goh

SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier
Selected by
18 September 2020
Theresa Pohlkamp

Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
Selected by
10 September 2020
Osvaldo Contreras, Nicolas Collao

Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex
Selected by
01 August 2020
Kristina Kuhbandner

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
31 July 2020
Yen-Chung Chen

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
25 July 2020
Zhang-He Goh, Josie Gibson

The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection
Selected by
25 July 2020
Zhang-He Goh

Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair
Selected by
24 July 2020
Julio Sainz de Aja

A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis
Selected by
15 July 2020
Snehal Kadam
