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A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

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Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

BAcTrace a new tool for retrograde tracing of neuronal circuits

Sebastian Cachero, Marina Gkantia, Alexander S. Bates, et al.

Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

Katrin Mangold, Jan Mašek, Jingyan He, et al.

Astrocytes and neurons share brain region-specific transcriptional signatures

Álvaro Herrero-Navarro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al.

Endogenous retroviruses drive species-specific germline transcriptomes in mammals

Akihiko Sakashita, So Maezawa, Kris G. Alavattam, et al.

Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses

Shengsheng Lu, Xiaoyan Pan, Daiwei Chen, et al.

Repairing neural damage in a C. elegans chemosensory circuit using genetically engineered synapses

Ithai Rabinowitch, Bishal Upadhyaya, Aaradhya Pant, et al.

Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells

Neal G. Ravindra, Mia Madel Alfajaro, Victor Gasque, et al.

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Robert J. Nims, Lara Pferdehirt, Noelani B. Ho, et al.

TMPRSS2 and TMPRSS4 mediate SARS-CoV-2 infection of human small intestinal enterocytes

Ruochen Zang, Maria F.G. Castro, Broc T. McCune, et al.