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Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics

Charlotte S. Sørensen, Magnus Kjaergaard

Over-activation of BMP signaling in neural crest cells precipitates heart outflow tract septation

Jean Francois Darrigrand, Mariana Valente, Pauline Martinez, et al.

Discussion

Spreading of molecular mechanical perturbations on linear filaments

Zsombor Balassy, Anne-Marie Lauzon, Lennart Hilbert

Discussion

Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression

Alexandra Despang, Robert Schöpflin, Martin Franke, et al.

Discussion

Engineered Enzymes that Retain and Regenerate their Cofactors Enable Continuous-Flow Biocatalysis

Carol J. Hartley, Charlotte C. Williams, Judith A. Scoble, et al.

Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins

Kelsey M. Tyssowski, Jesse M. Gray

Discussion

Crowdfunded whole-genome sequencing of the celebrity cat Lil BUB identifies causal mutations for her osteopetrosis and polydactyly

Mike Bridavsky, Heiner Kuhl, Arthur Woodruf, et al.

Slide-seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution

Samuel G Rodriques, Robert R Stickels, Aleksandrina Goeva, et al.

AND

High-density spatial transcriptomics arrays for in situ tissue profiling

Sanja Vickovic, Goekcen Eraslan, Johanna Klughammer, et al.

Discussion

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

Adam K. Glaser, Nicholas P. Reder, Ye Chen, et al.

Myc instructs and maintains pancreatic adenocarcinoma phenotype

Nicole M Sodir, Roderik M Kortlever, Valentin JA Barthet, et al.

Discussion

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Marion Regnier, Arnaud Polizzi, Sarra Smati, et al.

MicroRNA-mediated control of developmental lymphangiogenesis

Hyun Min Jung, Ciara Hu, Alexandra M Fister, et al.

Discussion