Search results

Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive inter- and intra-enhancer redundancy

A. Hörnblad, K. Langenfeld, S. Bastide, et al.

Selected by 25 March 2020

Clarice Hong

enhancers predominantly regulate gene expression in vivo via transcription initiation

Martin S. C. Larke, Takayuki Nojima, Jelena Telenius, et al.

Selected by 09 December 2019

Clarice Hong

Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications

María Touceda-Suárez, Elizabeth M. Kita, Rafael D. Acemel, et al.

Selected by 14 October 2019

Jesus Victorino

KMT5C displays robust retention and liquid-like behavior in phase separated heterochromatin

Hilmar Strickfaden, Kristal Missiaen, Michael J. Hendzel, et al.

Selected by 30 September 2019

Carmen Adriaens

A developmental gene regulatory network for invasive differentiation of the C. elegans anchor cell

Taylor N. Medwig-Kinney, Jayson J. Smith, Nicholas J. Palmisano, et al.

Selected by 05 August 2019

Sina Knapp

Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation

Masashi Yukawa, Sajjeev Jagannathan, Andrey V. Kartashov, et al.

Selected by 02 August 2019

Jonny Coates

Resolving the 3D landscape of transcription-linked mammalian chromatin folding

Tsung-Han S. Hsieh, Elena Slobodyanyuk, Anders S. Hansen, et al.

Selected by 13 June 2019

Clarice Hong

Discussion

A conserved regulatory program drives emergence of the lateral plate mesoderm

Karin D. Prummel, Christopher Hess, Susan Nieuwenhuize, et al.

Selected by 06 June 2019

Meng Zhu

Discussion

Developmentally regulated Shh expression is robust to TAD perturbations

Iain Williamson, Lauren Kane, Paul S. Devenney, et al.

Selected by 21 May 2019

Jesus Victorino

Oncogenic hijacking of a developmental transcription factor evokes therapeutic vulnerability for ROS-induction in Ewing sarcoma

Aruna Marchetto, Shunya Ohmura, Martin F. Orth, et al.

Selected by 12 April 2019

Hannah Brunsdon

Discussion

Preformed Chromatin Topology Assists Transcriptional Robustness of Shh during Limb Development

Christina Paliou, Philine Guckelberger, Robert Schöpflin, et al.

Selected by 08 April 2019

Rafael Galupa

Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression

Alexandra Despang, Robert Schöpflin, Martin Franke, et al.

Selected by 23 March 2019

Clarice Hong

Discussion