NINJA: an inducible genetic model for creating neoantigens in vivo
Selected by
Deborah Caswell
Loss of epithelial polarity redirects Notch signaling and triggers a Xrp1 response during neoplastic growth in Drosophila
Selected by
Sally Lowell
KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation
Selected by
Jonny Coates
Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors
Selected by
Vassilis Papalazarou, Anh Hoang Le
Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses
Selected by
Zhang-He Goh
Mechanotransduction of strain regulates an invasive phenotype in newly transformed epithelial cells
Selected by
William Hill
Axon-like protrusions promote small cell lung cancer migration and metastasis
Selected by
Pavithran Ravindran
The Wnt pathway scaffold protein Axin promotes signaling specificity by suppressing competing kinase reactions
Selected by
Yasmin Lau
Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching
Selected by
Hannah Brunsdon
Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types
Selected by
Jonny Coates
A unified role for membrane-cortex detachment during cell protrusion initiation
Selected by
Martim Dias Gomes
Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth
Selected by
Beverley Wilson