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NINJA: an inducible genetic model for creating neoantigens in vivo

Martina Damo, Brittany Fitzgerald, Yisi Lu, et al.



Selected by Deborah Caswell

Loss of epithelial polarity redirects Notch signaling and triggers a Xrp1 response during neoplastic growth in Drosophila

Rémi Logeay, Charles Géminard, Patrice Lassus, et al.



Selected by Sally Lowell

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation

Jasmine Li, Kristine Hardy, Moshe Olshansky, et al.



Selected by Jonny Coates

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Andrew Wishart, Yifan Peng, Sydney Conner, et al.



Selected by Vassilis Papalazarou, Anh Hoang Le

Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses

Chris J. de Witte, Jose Espejo Valle-Inclan, Nizar Hami, et al.



Selected by Zhang-He Goh

Mechanotransduction of strain regulates an invasive phenotype in newly transformed epithelial cells

Sophie Chagnon-Lessard, Hubert Jean-Ruel, Michel Godin, et al.



Selected by William Hill

Axon-like protrusions promote small cell lung cancer migration and metastasis

Dian Yang, Fangfei Qu, Hongchen Cai, et al.



Selected by Pavithran Ravindran

The Wnt pathway scaffold protein Axin promotes signaling specificity by suppressing competing kinase reactions

Maire Gavagan, Elizabeth Speltz, Jesse Zalatan



Selected by Yasmin Lau

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

Jasper Wouters, Zeynep Kalender-Atak, Liesbeth Minnoye, et al.



Selected by Hannah Brunsdon

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.



Selected by Jonny Coates

A unified role for membrane-cortex detachment during cell protrusion initiation

Erik S. Welf, Christopher E. Miles, Jaewon Huh, et al.



Selected by Martim Dias Gomes

Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth

Erin N. Howe, Miranda D. Burnette, Melanie E. Justice, et al.



Selected by Beverley Wilson

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