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An early cell shape transition drives evolutionary expansion of the human forebrain

Silvia Benito-Kwiecinski, Stefano L. Giandomenico, Magdalena Sutcliffe, et al.

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Discussion

SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways

Nataliia Serbyn, Ivona Bagdiul, Agnès H. Michel, et al.

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan Jahnel, Nora Papai, et al.

T cell receptor is required for differentiation but not maintenance of intestinal intraepithelial lymphocytes

Angelina M. Bilate, Mariya London, Tiago B. R. Castro, et al.

Discussion

Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure

Jerome AJ Becker, Lucie P Pellissier, Yannick Corde, et al.

Discussion

A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis

Vivek V. Thacker, Neeraj Dhar, Kunal Sharma, et al.

Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum

Thomas C. A. Blake, Silvia Haase, Jake Baum

systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Discussion

Epithelial Tissues as Active Solids: From Nonlinear Contraction Pulses to Rupture Resistance

Shahaf Armon, Matthew S. Bull, Avraham Moriel, et al.

Discussion

Lineage recording reveals dynamics of cerebral organoid regionalization

Zhisong He, Tobias Gerber, Ashley Maynard, et al.

Discussion

20 years of African Neuroscience: Waking a sleeping giant

MB Maina, U Ahmad, HA Ibrahim, et al.