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Biologically informed NeuralODEs for genome-wide regulatory dynamics

Intekhab Hossain, Viola Fanfani, John Quackenbush, et al.

Selected by 31 May 2023

Benjamin Dominik Maier

Bioinformatics

Coxiella burnetii actively blocks IL-17-induced oxidative stress in macrophages

Tatiana M. Clemente, Leonardo Augusto, Rajendra K. Angara, et al.

Selected by 16 May 2023

UofA IMB565

Microbiology

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by 15 May 2023

Jennifer Ann Black

Molecular Biology

Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor Regression

Adrian J. Luna, Jesse M. Young, Rosa T. Sterk, et al.

Selected by 14 May 2023

Yvonne Xinyi Lim

Cancer Biology

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.

Selected by 06 May 2023

Zhang-He Goh

Pharmacology and Toxicology

Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

Selected by 24 April 2023

Fiona Macleod

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley

Selected by 10 April 2023

Benjamin Dominik Maier

Systems Biology

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.

Selected by 07 April 2023

Benjamin Dominik Maier

Genomics

Flat clathrin lattices are linked to metastatic potential in colorectal cancer

Charlotte Cresens, Guillermo Solis-Fernandez, Astha Tiwari, et al.

Selected by 06 April 2023

Emily Chan

Biophysics

CTCF is essential for proper mitotic spindle structure and anaphase segregation

Katherine Chiu, Yasmin Berrada, Nebiyat Eskndir, et al.

Selected by 23 March 2023

Saanjbati Adhikari

Biochemistry
Alumni

marmite defines a novel conserved neuropeptide family mediating nutritional homeostasis

AP Francisco, I Tastekin, AB Fernandes, et al.

Selected by 22 March 2023

Pablo Ranea Robles, Cláudia Gil

Physiology

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.

Selected by 09 March 2023

Pierre Caron

Cancer Biology