Search results

High-throughput discovery and characterization of human transcriptional effectors

Josh Tycko, Nicole DelRosso, Gaelen T. Hess, et al.

CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice

L Caló, E Hidari, M Wegrzynowicz, et al.

High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells

Xiaowei Yan, Nico Stuurman, Susana A. Ribeiro, et al.

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Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization

Gil Kanfer, Shireen A. Sarraf, Yaakov Maman, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

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Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Discussion

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Discussion

BAcTrace a new tool for retrograde tracing of neuronal circuits

Sebastian Cachero, Marina Gkantia, Alexander S. Bates, et al.

Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

Katrin Mangold, Jan Mašek, Jingyan He, et al.

Discussion

Astrocytes and neurons share brain region-specific transcriptional signatures

Álvaro Herrero-Navarro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al.

Discussion

Endogenous retroviruses drive species-specific germline transcriptomes in mammals

Akihiko Sakashita, So Maezawa, Kris G. Alavattam, et al.

Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses

Shengsheng Lu, Xiaoyan Pan, Daiwei Chen, et al.

Discussion

Repairing neural damage in a C. elegans chemosensory circuit using genetically engineered synapses

Ithai Rabinowitch, Bishal Upadhyaya, Aaradhya Pant, et al.