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Mechanosensitive dynamics of lysosomes regulates the emergence of leader cells during collective cell migration

Rituraj Marwaha, Simran Rawal, Purnati Khuntia, et al.

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.

PHYtOMap: Multiplexed single-cell 3D spatial gene expression analysis in plant tissue

tatsuya Nobori, Marina Oliva, Ryan Lister, et al.

Discussion

DOt1L activity affects cell lineage progression in the developing brain by controlling metabolic programs

Bismark Appiah, Camilla L. Fullio, Christiane Haffner, et al.

Discussion

Diverse logics and grammar encode notochord enhancers

Benjamin P Song, Michelle F Ragsac, Krissie tellez, et al.

Multifunctional fluorophores for live-cell imaging and affinity capture of proteins

Pratik Kumar, Jason D. Vevea, Edwin R. Chapman, et al.

Discussion

MPS1 localizes to microtubule-attached kinetochores and actively promotes microtubule release

Daniel Hayward, Emile Roberts, Ulrike Gruneberg

A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

Yu Xin Wang, Colin A. Holbrook, James N. Hamilton, et al.

Discussion

tissue confinement regulates cell growth and size in epithelia

John Devany, Martin J. Falk, Liam J. Holt, et al.

Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP

James Chapman, Hanna Salmonowicz, Stella Victorelli, et al.

Discussion

Epistasis between promoter activity and coding mutations shapes gene evolvability

Angel F. Cisneros, Isabelle Gagnon-Arsenault, Alexandre K. Dubé, et al.