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Disrupting cellular memory to overcome drug resistance

Guillaume Harmange, Raúl A. Reyes Hueros, Dylan Schaff, et al.

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.

An intestinal sphingolipid promotes neuronal health across generations

Wenyue Wang, Tessa Sherry, Xinran Cheng, et al.

DOT1L activity affects cell lineage progression in the developing brain by controlling metabolic programs

Bismark Appiah, Camilla L. Fullio, Christiane Haffner, et al.

Discussion

Diverse logics and grammar encode notochord enhancers

Benjamin P Song, Michelle F Ragsac, Krissie Tellez, et al.

Morphodynamic Atlas for Drosophila Development

Noah P Mitchell, Matthew F Lefebvre, Vishank Jain-Sharma, et al.

The ELT-3 GATA factor specifies endoderm in Caenorhabditis angaria in an ancestral gene network

Gina Broitman-Maduro, Morris F. Maduro

The molecular architecture of cell cycle arrest

Wayne Stallaert, Sovanny R. Taylor, Katarzyna M. Kedziora, et al.

Periodic spatial patterning with a single morphogen

Sheng Wang, Jordi Garcia-Ojalvo, Michael B. Elowitz

Oligodendrocyte precursor cells engulf synaptic inputs in an experience- and microglia-dependent manner

Yohan S.S. Auguste, Austin Ferro, Jessica Dixon, et al.

Discussion

Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

Timo N. Kohler, Joachim De Jonghe, Anna L. Ellerman, et al.

Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells

Joseph L. Watson, Ariel J. Ben-Sasson, Alice Bittleston, et al.