Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance
Selected by
UofA IMB565
Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine
Selected by
Zhang-He Goh
Discovery and visualization of uncharacterized drug-protein adducts using mass spectrometry
Selected by
Zhang-He Goh
Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics
Selected by
Afonso Mendes
Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors
Selected by
Zhang-He Goh
Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice
Selected by
Zhang-He Goh
Pharmacological Insights into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure
Selected by
Zhang-He Goh
Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype
Selected by
Zhang-He Goh
Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports
AND
Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia
Selected by
Zhang-He Goh
Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism
Selected by
Zhang-He Goh
A therapeutic combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite
Selected by
Zhang-He Goh
Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses
Selected by
Zhang-He Goh