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Carmen Adriaens

Harvard Medical School, The Broad Institute and Massachusetts General Hospital

I am a postdoc in the Bernstein lab at MGH/HMS in Boston where I study chromatin in cancer cells.

I did my Ph.D. on non-coding RNA in cancer in the lab of Chris Marine at the CCB (VIB-KU Leuven) in Belgium, and spent some time in the Steve Jackson Lab in Cambridge, UK, and the Misteli Lab at the NCI in Bethesda, USA during this time.

My scientific interests are non-coding RNA, nuclear bodies, mouse models & genetics, nuclear topology/chromatin conformation, phase separation, and gene expression/transcription. I’m most likely to post about these, but I am fascinated by many things in the biological world so it could be just as well any other random topic I really like or stumbled upon!

Apart from science, I love great food, contemporary dance, and people (I think everybody has a ‘thing’ and I like to discover that!).

Carmen Adriaens has added 13 preLight posts

KMT5C displays robust retention and liquid-like behavior in phase separated heterochromatin

Hilmar Strickfaden, Kristal Missiaen, Michael J. Hendzel, et al.



Selected by Carmen Adriaens

Slide-seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution

Samuel G Rodriques, Robert R Stickels, Aleksandrina Goeva, et al.

AND

High-density spatial transcriptomics arrays for in situ tissue profiling

Sanja Vickovic, Goekcen Eraslan, Johanna Klughammer, et al.



Selected by Carmen Adriaens

SorCS1-mediated Sorting of Neurexin in Dendrites Maintains Presynaptic Function

Luis Filipe Ribeiro, Ben Verpoort, Julie Nys, et al.



Selected by Carmen Adriaens

Promoter-intrinsic and local chromatin features determine gene repression in lamina-associated domains

Christ Leemans, Marloes van der Zwalm, Laura Brueckner, et al.



Selected by Carmen Adriaens, Clarice Hong

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian Kopp, Mehmet Yalvac, Beibei Chen, et al.



Selected by Carmen Adriaens

Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Silvia Bonàs-Guarch, Inês Cebola, et al.



Selected by Carmen Adriaens

Nuclear pore density controls heterochromatin reorganization during senescence

Charlene Boumendil, Priya Hari, Karl Olsen, et al.



Selected by Carmen Adriaens

SWI/SNF remains localized to chromatin in the presence of SCHLAP1

Jesse R Raab, Keriayn N Smith, Camarie C Spear, et al.



Selected by Carmen Adriaens

Live-cell imaging of marked chromosome regions reveals dynamics of mitotic chromosome resolution and compaction

John K Eykelenboom, Marek Gierlinski, Zuojun Yue, et al.

AND

Quantitative imaging of chromatin decompaction in living cells

Elisa Dultz, Roberta Mancini, Guido Polles, et al.



Selected by Carmen Adriaens, Dey Lab

PDX Finder: A Portal for Patient-Derived tumor Xenograft Model Discovery

Nathalie Conte, Jeremy Mason, Csaba Halmagyi, et al.



Selected by Carmen Adriaens

Higher-Order Organization Principles of Pre-translational mRNPs

Mihir Metkar, Hakan Ozadam, Bryan R. Lajoie, et al.



Selected by Carmen Adriaens

A role for RNA and DNA:RNA hybrids in the modulation of DNA repair by homologous recombination

Giuseppina D'Alessandro, Marek Adamowicz, Donna Whelan, et al.



Selected by Carmen Adriaens

Carmen Adriaens has collaborated with:

Carmen Adriaens has commented 1 time

5 years

Carmen Adriaens

Hi Theo! Awesome highlight. I look forward to see higher resolution examples of this technique in the future, and I’m generally excited about non-genetic applications for DNA techniques!

As relating to the third paper you mention, you can take a look at this one, too: https://www.biorxiv.org/content/early/2018/08/02/383943

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