Capturing the onset of PRC2-mediated repressive domain formation

A DNA-based voltmeter for organelles

Anand Saminathan, John Devany, Kavya S Pillai, et al.

Structures of the Otopetrin Proton Channels Otop1 and Otop3

Kei Saotome, Bochuan Teng, Che Chun (Alex) Tsui, et al.

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate desmosome assembly and cell adhesion.

Keith T Woodley, Mark O Collins

3

A complex containing lysine-acetylated actin inhibits the formin INF2

Mu A, Tak Shun Fung, Arminja N. Kettenbach, et al.

1

Super-resolution Molecular Map of Basal Foot Reveals Novel Cilium in Airway Multiciliated Cells

Quynh Nguyen, Zhen Liu, Rashmi Nanjundappa, et al.

Atlas of Subcellular RNA Localization Revealed by APEX-seq

Furqan M Fazal, Shuo Han, Pornchai Kaewsapsak, et al.

AND

Proximity RNA labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules

Alejandro Padron, Shintaro Iwasaki, Nicholas Ingolia

Applications, Promises, and Pitfalls of Deep Learning for Fluorescence Image Reconstruction

Chinmay Belthangady , Loic A. Royer

Activation of intracellular transport by relieving KIF1C autoinhibition

Nida Siddiqui, Alice Bachmann, Alexander J Zwetsloot, et al.

1

Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis

Jonathan P Gumucio, Austin H Qasawa, Patrick J Ferrara, et al.

Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

Diego Gauto, Leandro Estrozi, Charles Schwieters, et al.

1

Disrupting Transcriptional Feedback Yields an Escape-Resistant Antiviral

Sonali Chaturvedi, Marie Wolf, Noam Vardi, et al.

1

Structure of a cytochrome-based bacterial nanowire

David J Filman, Stephen F Marino, Joy E Ward, et al.

Multi-color single molecule imaging uncovers extensive heterogeneity in mRNA decoding

Sanne Boersma, Deepak Khuperkar, Bram M.P. Verhagen, et al.

AND

Live-cell single RNA imaging reveals bursts of translational frameshifting

Kenneth R Lyon Jr, Luis U Aguilera, Tatsuya Morisaki, et al.

Retrieving High-Resolution Information from Disordered 2D Crystals by Single Particle Cryo-EM

Ricardo Righetto, Nikhil Biyani, Julia Kowal, et al.

Structural venomics: evolution of a complex chemical arsenal by massive duplication and neofunctionalization of a single ancestral fold

Sandy Steffany Pineda, Yanni K-Y Chin, Eivind A.B. Undheim, et al.

Synthetic pluripotent bacterial stem cells

Sara Molinari, David L. Shis, James Chappell, et al.

A DNA-based voltmeter for organelles

Anand Saminathan, John Devany, Kavya S Pillai, et al.

Central spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B

Che-Hang Yu, Stefanie Redemann, Hai-Yin Wu, et al.

1

Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division

Evgeny Zatulovskiy, Daniel F. Berenson, Benjamin R. Topacio, et al.

1

Minimal membrane interactions conferred by Rheb C-terminal farnesylation are essential for mTORC1 activation

Shawn M Ferguson, Brittany Angarola

Mechanical Stretch Kills Transformed Cancer Cells

Ajay Tijore, Mingxi Yao, Yu-Hsiu Wang, et al.

EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake

Claudia Matthaeus, Ines Lahmann, Severine Kunz, et al.

1

Mechanical Stretch Kills Transformed Cancer Cells

Ajay Tijore, Mingxi Yao, Yu-Hsiu Wang, et al.

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart

Hessel Honkoop, Dennis de Bakker, Alla Aharonov, et al.

1

S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate desmosome assembly and cell adhesion.

Keith T Woodley, Mark O Collins

3

A complex containing lysine-acetylated actin inhibits the formin INF2

Mu A, Tak Shun Fung, Arminja N. Kettenbach, et al.

1

Super-resolution Molecular Map of Basal Foot Reveals Novel Cilium in Airway Multiciliated Cells

Quynh Nguyen, Zhen Liu, Rashmi Nanjundappa, et al.

Single cell RNA-Seq reveals distinct stem cell populations that drive sensory hair cell regeneration in response to loss of Fgf and Notch signaling

Mark E. Lush, Daniel C. Diaz, Nina Koenecke, et al.

AND

Distinct progenitor populations mediate regeneration in the zebrafish lateral line.

Eric D Thomas, David Raible

1

Actomyosin-II facilitates long-range retrograde transport of large cargoes by controlling axonal radial contractility

Tong Wang, Wei Li, Sally Martin, et al.

Atlas of Subcellular RNA Localization Revealed by APEX-seq

Furqan M Fazal, Shuo Han, Pornchai Kaewsapsak, et al.

AND

Proximity RNA labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules

Alejandro Padron, Shintaro Iwasaki, Nicholas Ingolia

High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue-specificity

Kaia Mattioli, Pieter-Jan Volders, Chiara Gerhardinger, et al.

Reconstruction of the global neural crest gene regulatory network in vivo

Ruth M Williams, Ivan Candido-Ferreira, Emmanouela Repapi, et al.

Charting a tissue from single-cell transcriptomes

Mor Nitzan, Nikos Karaiskos, Nir Friedman, et al.

Single cell RNA-Seq reveals distinct stem cell populations that drive sensory hair cell regeneration in response to loss of Fgf and Notch signaling

Mark E. Lush, Daniel C. Diaz, Nina Koenecke, et al.

AND

Distinct progenitor populations mediate regeneration in the zebrafish lateral line.

Eric D Thomas, David Raible

1

Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan

Julien Rougot, Naomi D Chrispijn, Marco Aben, et al.

1

The embryonic transcriptome of Arabidopsis thaliana

Falko Hofmann, Michael A Schon, Michael D Nodine

1

Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells

Mridusmita Saikia, Philip Burnham, Sara H Keshavjee, et al.

AND

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Mandeep Singh, Ghamdan Al-Eryani, Shaun Carswell, et al.

The microbial basis of impaired wound healing: differential roles for pathogens, "bystanders", and strain-level diversification in clinical outcomes

Lindsay Kalan, Jacquelyn S Meisel, Michael A Loesche, et al.

Comparative analysis of droplet-based ultra-high-throughput single-cell RNA-seq systems

Xiannian Zhang, Tianqi Li, Feng Liu, et al.

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian Kopp, Mehmet Yalvac, Beibei Chen, et al.

LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy

Susanne Nichterwitz, Helena Storvall, Jik Nijssen, et al.

AND

Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

Jik Nijssen, Julio Cesar Aguila Benitez, Rein Hoogstraaten, et al.

LADL: Light-activated dynamic looping for endogenous gene expression control

Mayuri Rege, Ji Hun Kim, Jacqueline Valeri, et al.

Precise tuning of gene expression output levels in mammalian cells

Yale S. Michaels, Mike B Barnkob, Hector Barbosa, et al.

1

Template switching causes artificial junction formation and false identification of circular RNAs

Chong Tang, Tian Yu, Yeming Xie, et al.

The genomic basis of colour pattern polymorphism in the harlequin ladybird

Mathieu Gautier, Junichi Yamaguchi, Julien Foucaud, et al.

Widespread inter-individual gene expression variability in Arabidopsis thaliana

Sandra Cortijo, Zeynep Aydin, Sebastian Ahnert, et al.

A DNA-based voltmeter for organelles

Anand Saminathan, John Devany, Kavya S Pillai, et al.

Structures of the Otopetrin Proton Channels Otop1 and Otop3

Kei Saotome, Bochuan Teng, Che Chun (Alex) Tsui, et al.

Central spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B

Che-Hang Yu, Stefanie Redemann, Hai-Yin Wu, et al.

1

Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division

Evgeny Zatulovskiy, Daniel F. Berenson, Benjamin R. Topacio, et al.

1

Distinct ROPGEFs successively drive polarization and outgrowth of root hairs

Philipp Denninger, Anna Reichelt, Vanessa Aphaia Fiona Schmidt, et al.

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

Bacteriophage resistance alters antibiotic mediated intestinal expansion of enterococci

Anushila Chatterjee, Cydney N Johnson, Phat Luong, et al.

On-site ribosome remodeling by locally synthesized ribosomal proteins in axons

Toshiaki Shigeoka, Max Koppers, Hovy Ho-Wai Wong, et al.

MRE11-RAD50-NBS1 activates Fanconi Anemia R-loop suppression at transcription-replication conflicts

Emily Yun-Chia Chang, James P Wells, Shu-Huei Tsai, et al.

1

Super-resolution Molecular Map of Basal Foot Reveals Novel Cilium in Airway Multiciliated Cells

Quynh Nguyen, Zhen Liu, Rashmi Nanjundappa, et al.

Atlas of Subcellular RNA Localization Revealed by APEX-seq

Furqan M Fazal, Shuo Han, Pornchai Kaewsapsak, et al.

AND

Proximity RNA labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules

Alejandro Padron, Shintaro Iwasaki, Nicholas Ingolia

Unlimited genetic switches for cell-type specific manipulation

Jorge Garcia-Marques, Ching-Po Yang, Isabel Espinosa-Medina, et al.

1

Stable knockout and complementation of receptor expression using in vitro cell line derived reticulocytes for dissection of host malaria invasion requirements

Timothy J Satchwell, Katherine E Wright, Katy L Haydn-Smith, et al.

The coordination of terminal differentiation and cell cycle exit is mediated through the regulation of chromatin accessibility

Yiqin Ma, Daniel J McKay, Laura Buttitta

1

Disrupting Transcriptional Feedback Yields an Escape-Resistant Antiviral

Sonali Chaturvedi, Marie Wolf, Noam Vardi, et al.

1

Multi-color single molecule imaging uncovers extensive heterogeneity in mRNA decoding

Sanne Boersma, Deepak Khuperkar, Bram M.P. Verhagen, et al.