preLights peer support – preprints of interest

How to reach out to contribute (either to suggest preprints OR to write a preLight)? 
preLighters: slack DMs
others: email to girish.kale [at] uni-hohenheim.de OR use the Contact form above. In either case, please add ‘preLights peer support’ in the subject line.

What all information is available in this preList?
This preList contains various interesting preprints. Each preprint will carry a bunch of keywords: these could be from the preprint itself, or additional ones based on a quick reading of the manuscript.

How is the preList page organised?
The preprints are sorted reverse-chronologically (latest preprints on the top). Ideally, the preprints at the top should be preferred over the older ones, though, if you find an older preprint to be really interesting, feel free to reach out to check if it can still be added to the preList, or highlighted if already in the preList. Keep in mind that, sooner or later the old preprints will be published, and can’t be highlighted through preLights anymore.

2024 July

Control of Modular Tissue Flows Shaping the Embryo in Avian Gastrulation

Guillermo Serrano Nájera, Alex M Plum, Benjamin Steventon, Cornelis J Weijer, Mattia Serra

https://www.biorxiv.org/content/10.1101/2024.07.04.601785v1

Developmental biology, Dynamic Morphoskeleton, active matter physics, attractors vs. repellers, intercalation, myosin contractility, chicken embryo

Ecology not genetics explains correlated trait divergence during speciation

Clarissa F. de Carvalho, Nicholas P. Planidin, Romain Villoutreix, Víctor Soria-Carrasco, Rüdiger Riesch, Jeffrey L. Feder, Thomas L. Parchman, Jon Slate, Zachariah Gompert, Patrik Nosil

https://www.biorxiv.org/content/10.1101/2024.07.02.601691v1

Evolutionary biology, genetic covariance, environmental alignment, ecological speciation, sexual selection, Timema stick-insects

Substrate Rigidity Modulates Segmentation Clock Dynamics in Isolated Presomitic Mesoderm Cells

Chun-Yen Sung, Usha Kadiyala, Owen Blanchard, Liam Yourston, Derek Walker, Linyuan Li, Jianping Fu, Qiong Yang

https://www.biorxiv.org/content/10.1101/2024.07.02.601712v1

Developmental biology, Segmentation clock, somitogenesis, oscillator, presomitic mesoderm, surface rigidity

Genetic architecture of the thermal tolerance landscape of Drosophila melanogaster

Juan Soto, Francisco Pinilla, Patricio Olguín, Luis E. Castañeda

https://www.biorxiv.org/content/10.1101/2024.07.01.601629v1

Evolutionary biology, DGRP, heritability, adaptation, CTmax, TDT curves

2024 June

Control of epiblast cell fate by mechanical cues

Charlène Guillot, Yannis Djeffal, Mattia Serra, Olivier Pourquié

https://www.biorxiv.org/content/10.1101/2024.06.24.600402v1

Developmental biology, scRNAseq, linear tracing, mechanical constraints, chicken embryo

Ecdysteroid-dependent molting in tardigrades

Shumpei Yamakawa, Andreas Hejnol

https://www.biorxiv.org/content/10.1101/2024.06.14.599130v1

Developmental biology, Ecdysozoa, regulation of molting, Hypsibius exemplaris

Redistribution of fragmented mitochondria ensure symmetric organelle partitioning and faithful chromosome segregation in mitotic mouse zygotes

Haruna Gekko, Ruri Nomura, Daiki Kuzuhara, Masato Kaneyasu, Genpei Koseki, Deepak Adhikari, Yasuyuki Mio, John Carroll, Tomohiro Kono, Hiroaki Funahashi, Takuya Wakai

https://www.biorxiv.org/content/10.1101/2024.06.13.598818v1

Developmental biology, Mitochondrial dynamics, dynamin-related protein 1, embryo cleavage, preimplantation development, organelle inheritance, ER calcium stores, chromosome segregation, binuclear formation, assisted reproductive technologies

Experimental evolution under combined thermal-nutritional stress in Drosophila melanogaster results in evolved shifts in larval thermotolerance and thermal plasticity

Yeuk Man Movis Choy, Teresa Kutz, Fiona E. Cockerell, Emily Lombardi, Sandra Hangartner, Christen K. Mirth, Carla M. Sgrò

https://www.biorxiv.org/content/10.1101/2024.06.12.598748v1

Evolutionary biology, experimental evolution, thermal tolerance, climate change, hardening, heat, cold, acute shock, viability, phenotypic plasticity

Glycolytic Disruption Triggers Interorgan Signaling to Nonautonomously Restrict Drosophila Larval Growth

Madhulika Rai, Hongde Li, Robert A. Policastro, Gabriel E. Zentner, Travis Nemkov, Angelo D’Alessandro, Jason M. Tennessen

https://www.biorxiv.org/content/10.1101/2024.06.06.597835v2

Developmental biology, metabolism, glycolysis, inter-organ communication, ecdysone, Drosophila melanogaster

Hypoxia-Sonic Hedgehog Axis as a Driver of Primitive Hematopoiesis Development and Evolution in Cavefish

Corine M. van der Weele, Katrina C. Hospes, Katherine E. Rowe, William R. Jeffery

https://www.biorxiv.org/content/10.1101/2024.06.09.598120v1

Developmental biology, primitive hematopoiesis, erythrocyte development, evolution, hypoxia, Sonic hedgehog, Astyanax mexicanus, cavefish

Systematic analysis of protein stability associated with species-specific developmental tempo

Mitsuhiro Matsuda, Henrik M. Hammarén, Jorge Lázaro, Mikhail M. Savitski, Miki Ebisuya

https://www.biorxiv.org/content/10.1101/2024.06.07.597977v1

Developmental biology, segmentation, clock period, Human vs. Mouse, SILAC-based proteomics, metabolism, glycolysis

Metabolic activities are selective modulators for individual segmentation clock processes

Mitsuhiro Matsuda, Jorge Lázaro, Miki Ebisuya

https://www.biorxiv.org/content/10.1101/2024.06.04.597451v1

Developmental biology, segmentation, clock period, metabolism, glycolysis, electron transport chain, ATP synthesis, temperature

2024 May

Target gene responses differ when transcription factor levels are acutely decreased by nuclear export versus degradation

James McGehee, Angelike Stathopoulos

https://www.biorxiv.org/content/10.1101/2024.05.20.595009v1

Developmental biology, Dorsal, dorso-ventral axis patterning, snail, short-gastrulation, optogenetics, Drosophila

Deep-Tissue Spatial Omics: Imaging Whole-Embryo Transcriptomics and Subcellular Structures at High Spatial Resolution

Valentina Gandin, Jun Kim, Liang-Zhong Yang, Yumin Lian, Takashi Kawase, Amy Hu, Konrad Rokicki, Greg Fleishman, Paul Tillberg, Alejandro Aguilera Castrejon, Carsen Stringer, Stephan Preibisch, Zhe J. Liu

https://www.biorxiv.org/content/10.1101/2024.05.17.594641v1

Developmental biology, cycleHCR, expansion microscopy, E6.5~7.0 mouse embryo

Cell-matrix force transmission regulates the loss of naïve pluripotency in mouse embryonic stem cells

Srivatsava Viswanadha, Manuel Gómez-González, Celine Labouesse, Valeria Venturini, Xavier Trepat, Kevin Chalut, Zanetta Kechagia, Pere Roca-Cusachs

https://www.biorxiv.org/content/10.1101/2024.05.13.593501v1

Developmental biology, cell differentiation, traction force microscopy, GSK3-mediated signalling, mouse ESCs

Phased ERK-responsiveness and developmental robustness regulate teleost skin morphogenesis

Nitya Ramkumar, Christian Richardson, Makinnon O’Brien, Faraz Ahmed Butt, Jieun Park, Anna T Chao, Michel Bagnat, Kenneth Poss, Stefano Di Talia

https://www.biorxiv.org/content/10.1101/2024.05.13.593750v1

Developmental biology, imaging and quantitative analysis, cell division orientation, zebrafish

Temporal and anteriorly positioned mitotic zones drive asymmetric microtubule patterns needed for Left-Right Organizer development

Yan Wu, Yiling Lan, Favour Ononiwu, Abigail Poole, Kirsten Rasmussen, Jonah Da Silva, Abdalla Wael Shamil, Li-En Jao, Heidi Hehnly

https://www.biorxiv.org/content/10.1101/2024.05.12.593765v1

Developmental biology, left-right asymmetry, cell proliferation, zebrafish

Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation

Nicholas M. Cronin, Logan W. Dawson, Kris A. DeMali

https://www.biorxiv.org/content/10.1101/2024.05.09.593171v1

Cell biology, energy homeostasis, cell-cell adhesion

Endogenous OptoRhoGEFs reveal biophysical principles of epithelial tissue furrowing

Andrew D. Countryman, Caroline A. Doherty, R. Marisol Herrera-Perez, Karen E. Kasza

https://www.biorxiv.org/content/10.1101/2024.05.12.593711v1

Developmental biology, iLID/Sspb optogenetic system, CRISPR/Cas9, Drosphila

Noninvasive time-lapse 3D subcellular analysis of embryo development for machine learning-enabled prediction of blastocyst formation

Chungha Lee, Geon Kim, Taeseop Shin, Sangho Lee, Jae Young Kim, Kyoung Hee Choi, Jieun Do, Jaehyeong Park, Jaephil Do, Ji Hyang Kim, YongKeun Park

https://www.biorxiv.org/content/10.1101/2024.05.07.592317v1

Developmental biology, in-vitro fertilisation, label-free imaging, non-invasive imaging, quantitative phase imaging, mouse model

E-cadherin tunes tissue mechanical behavior before and during morphogenetic tissue flows

Xun Wang, Christian M. Cupo, Sassan Ostvar, Andrew D. Countryman, Karen E. Kasza

https://www.biorxiv.org/content/10.1101/2024.05.07.592778v1

Developmental biology, convergent-extension movements, Drosophila

2024 April

Cell rearrangement progression along the apical-basal axis is linked with 3D epithelial tissue structure

Erika M. Kusaka, Sassan Ostvar, Xun Wang, Xiaoyun Liu, Karen E. Kasza

https://www.biorxiv.org/content/10.1101/2024.04.29.591620v1

Developmental biology, Drosophila, germband extension, convergent extension, apical-basal polarity, epithelial morphogenesis, tissue remodeling

Thermal tolerance of mosquito eggs is associated with urban adaptation and human interactions

Souvik Chakraborty, Emily Zigmond, Sher Shah, Massamba Sylla, Jewelna Akorli, Sampson Otoo, Noah H. Rose, Carolyn S. McBride, Peter A. Armbruster, Joshua B. Benoit

https://www.biorxiv.org/content/10.1101/2024.03.22.586322v2

Ecology, mosquitoes, Aedes sp., human density, egg survival, heat tolerance, egg hatching index, ecological correlation

Single-embryo metabolomics reveals developmental metabolism in the early Drosophila embryo

J. Eduardo Pérez-Mojica, Zachary B. Madaj, Christine N. Isaguirre, Joe Roy, Kin H. Lau, Ryan D. Sheldon, Adelheid Lempradl

https://www.biorxiv.org/content/10.1101/2024.04.17.589796v1

Developmental biology

The Fat/Hippo pathway drives photoperiod-induced wing length polyphenism

Erik Gudmunds, Aleix Palahí, David Armisén, Douglas G. Scofield, Freya Darling Eriksen, Abderrahman Khila, Arild Husby

https://www.biorxiv.org/content/10.1101/2024.04.05.588279v1

Evolutionary biology, non-model species, water strider, Gerris buenoi

Tissue-level integration overrides gradations of differentiating cell identity in beetle extraembryonic tissue

Katie E. Mann, Kristen A. Panfilio

https://www.biorxiv.org/content/10.1101/2024.04.10.588827v1

Developmental biology, extraembryonic tissues; tissue differentiation; insects; polyploidy; RNAi; quantitative live imaging

Application of tissue-scale tension to avian epithelia in vivo to study multiscale mechanical properties and inter-germ layer coupling

Panagiotis Oikonomou, Lisa Calvary, Helena C. Cirne, Andreas E. Welch, John F. Durel, Olivia Powell, Nandan L. Nerurkar

https://www.biorxiv.org/content/10.1101/2024.04.04.588089v1

Developmental biology, epithelial mechanics, chick, endoderm, neurulation, cell morphometry

Nuclear deformability facilitates apical nuclear migration in the developing zebrafish retina

Mariana Maia-Gil, Maria Gorjão, Roman Belousov, Jaime A. Espina, João Coelho, Ana P. Ramos, Elias H. Barriga, Anna Erzberger, Caren Norden

https://www.biorxiv.org/content/10.1101/2024.04.04.588091v1

Developmental biology, nuclear lamins, zebrafish

2024 March

Mixed clonal-aggregative multicellularity entrained by extreme salinity fluctuations in a close relative of animals

Núria Ros-Rocher, Josean Reyes-Rivera, Yeganeh Foroughijabbari, Chantal Combredet, Ben T. Larson, Maxwell C. Coyle, Erik A.T. Houtepen, Mark J. A. Vermeij, Nicole King, Thibaut Brunet

https://www.biorxiv.org/content/10.1101/2024.03.25.586565v1

Evolutionary biology, evolution of multicellularity, Choanoflagellates

A novel protein Moat prevents ectopic epithelial folding by limiting Bazooka/Par3-dependent adherens junctions

Lingkun Gu, Rolin Sauceda, Jasneet Brar, Ferdos Fessahaye, Minsang Joo, Joan Lee, Jacqueline Nguyan, Marissa Teng, Mo Weng

https://www.biorxiv.org/content/10.1101/2024.03.05.583570v1

Developmental biology, Apical constriction; Patterning; Adherens junctions; Bazooka/Par3; Myosin; morphogenesis

Characterization of early and late events of adherens junction assembly

Regina B. Troyanovsky, Indrajyoti Indra, Sergey M. Troyanovsky

https://www.biorxiv.org/content/10.1101/2024.03.04.583373v1

Cell biology, a-catenin, vinculin, cadherin-catenin complex, binding to actin, adherens junctions

2024 February

Thermal plasticity in protective wing pigmentation is modulated by genotype and food availability in an insect model of seasonal polyphenism

E van Bergen, G Atencio, M Saastamoinen, P Beldade

https://www.biorxiv.org/content/10.1101/2024.02.26.582119v1

Developmental biology, developmental plasticity; non-additive environmental interactions; environmental epistasis; variation in reaction norms; thermal and nutritional environment; insect pigmentation; butterfly eyespots

Gene expression differences associated with intrinsic hindfoot muscle loss in the jerboa, Jaculus jaculus

Mai P. Tran, Daniel Ochoa Reyes, Alexander J. Weitzel, Aditya Saxena, Michael Hiller, Kimberly L. Cooper

https://www.biorxiv.org/content/10.1101/2024.02.20.581295v1

Developmental biology, limb development, comparative approaches, non-model species, Jerboa, Jaculus jaculus

An analysis of contractile and protrusive cell behaviours at the superficial surface of the zebrafish neural plate

Claudio Araya, Raegan Boekemeyer, Francesca Farlie, Lauren Moon, Freshta Darwish, Chris Rookyard, Leanne Allison, Gema Vizcay-Barrena, Roland Fleck, Millaray Aranda, Masa Tada, Jonathan D W Clarke

https://www.biorxiv.org/content/10.1101/2024.02.20.581322v1

Developmental biology, neural plate internalisation, morphogenetic movements, zebrafish

Long-term dynamics of adaptation to a warming environment is dependent on historical background

Marta A. Antunes, Afonso Grandela, Margarida Matos, Pedro Simões

https://www.biorxiv.org/content/10.1101/2024.02.15.580572v2

Evolutionary biology, Thermal adaptation, Experimental evolution, Long-term evolution, Climate change, Fertility, Drosophila

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate early mesoderm development

James F Clark, Philippe Soriano

https://www.biorxiv.org/content/10.1101/2024.02.16.580629v1

Developmental biology, FGF, mesoderm development, kidney development, cell signaling, cell adhesion, endocytic trafficking

A tension-induced morphological transition shapes the avian extra-embryonic territory

Arthur Michaut, Alexander Chamolly, Aurelien Villedieu, Francis Corson, Jerome Gros

https://www.biorxiv.org/content/10.1101/2024.02.08.579502v1

Developmental biology, extraembryonic tissue

Compressive stress drives morphogenetic apoptosis

Tatiana Merle, Martine Cazales, Ronan Bouzignac, Brice Ronsin, Christian Rouviere, Magali Suzanne

https://www.biorxiv.org/content/10.1101/2024.02.08.579454v1

Developmental biology, leg disk morphogenesis, Drosophila

Identifying the molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish

Simaran Johal, Randa Elsayed, Kristen A. Panfilio, Andrew C Nelson

https://www.biorxiv.org/content/10.1101/2024.02.06.579092v2

Developmental biology

Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis

Alyssa A Emig, Megan Hansen, Sandra Grimm, Cristian Coarfa, Nathan D Lord, Margot Kossmann Williams

https://www.biorxiv.org/content/10.1101/2024.02.06.579243v1

Developmental biology, Gastrulation, Morphogenesis, Convergent extension, Zebrafish, Nodal, BMP

Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination

Uzuki Horo, Nat Clarke, Adam C. Martin

https://www.biorxiv.org/content/10.1101/2024.02.02.578601v1

Developmental biology, mesoderm invagination, apical constriction

2024 January

The Lifeact-EGFP Quail: A New Avian Model For Studying Actin Dynamics In Vivo

https://www.biorxiv.org/content/10.1101/2023.11.19.567639v2

Developmental biology, non-model organisms, transgenics

Establishment of CRISPR/Cas9-based knock-in in a hemimetabolous insect: targeted gene tagging in the cricket Gryllus bimaculatus

Yuji Matsuoka, Taro Nakamura, Takahito Watanabe, Austen A. Barnett, Sayuri Tomonari, Guillem Ylla, Carrie A. Whittle, Sumihare Noji, Taro Mito, Cassandra G. Extavour

https://www.biorxiv.org/content/10.1101/2021.05.10.441399v2

Developmental biology, CRISPR/Cas9, Orthoptera, genome editing, Hox genes, Ultrabithorax, abdominal-A

Glycolysis–Wnt signaling axis tunes developmental timing of embryo segmentation

Hidenobu Miyazawa, Jona Rada, Paul Gerald Layague Sanchez, Emilia Esposito, Daria Bunina, Charles Girardot, Judith Zaugg, Alexander Aulehla

https://www.biorxiv.org/content/10.1101/2024.01.22.576629v2

Developmental biology, glycolysis, metabolism, Wnt signalling, segmentation

Development and patterning of a highly versatile visual system in spiders

Luis Baudouin Gonzalez, Anna Schoenauer, Amber Harper, Saad Arif, Daniel J Leite, Philip O. M. Steinhoff, Matthias Pechmann, Valeriia Telizhenko, Atal Pande, Carolin Kosiol, Alistair P McGregor, Lauren Sumner-Rooney

https://www.biorxiv.org/content/10.1101/2023.12.22.572789v3

Developmental biology, development and patterning in spiders

2023 December

Cell density couples tissue mechanics to control the elongation speed of the body axis

Changqing Lu, Joana M. N. Vidigueira, Christopher Chan Jin Jie, Alicja Maksymiuk, Fengzhu Xiong

https://www.biorxiv.org/content/10.1101/2023.12.31.573670v1

Developmental biology, segmentation, presomitic mesoderm, cell density, FGF signalling

Apical constriction requires patterned apical surface remodeling to synchronize cellular deformation

Satoshi Yamashita, Shuji Ishihara, François Graner

https://www.biorxiv.org/content/10.1101/2023.12.19.572310v1

Developmental biology, tissue folding, endocytosis, mechanical modelling

EGFR-dependent actomyosin patterning coordinates morphogenetic movements between tissues

D. Nathaniel Clarke, Adam Martin

https://www.biorxiv.org/content/10.1101/2023.12.22.573057v1

Developmental biology, mesoderm, ectoderm, cell adhesion, E-cadherin, EGFR signalling, Drosophila

Natural reversal of cavefish heart asymmetry is controlled by Sonic Hedgehog effects on the left-right organizer

Mandy Ng, Li Ma, Janet Shi, William R. Jeffery

https://www.biorxiv.org/content/10.1101/2023.12.13.571559v1

Developmental biology, cavefish, heart asymmetry, Sonic Hedgehog, left-right organizer, dand5 asymmetry

Mechanical strengthening of cell-cell adhesion during mouse embryo compaction

Ludmilla de Plater, Julie Firmin, Jean-Léon Maître

https://www.biorxiv.org/content/10.1101/2023.12.07.570568v1

Developmental biology, embryo compaction, cell adhesion, E-cadherin, dual pipette aspiration assay, mouse embryos

A temporal allocation of amino acid resources ensures fitness and body allometry

Luca Valzania, Aya Alami, Pierre Léopold

https://www.biorxiv.org/content/10.1101/2023.12.08.570599v1

Developmental biology, nutrition, growth, allometry, hexamerin, Drosophila

Revisiting bicoid function: complete inactivation reveals an additional fundamental role in Drosophila egg geometry specification

Stefan Baumgartner

https://www.biorxiv.org/content/10.1101/2023.12.08.570753v1

Developmental biology, bicoid, CRISPR, embryo geometry, Drosophila melanogster

Integrated Molecular-Phenotypic Profiling Reveals Metabolic Control of Morphological Variation in Stembryos

Alba Villaronga Luque, Ryan G Savill, Natalia López-Anguita, Adriano Bolondi, Sumit Garai, Seher Ipek Gassaloglu, Aayush Poddar, Aydan Bulut-Karslioglu, Jesse V Veenvliet

https://www.biorxiv.org/content/10.1101/2023.12.04.569921v1

Developmental biology, embryo models, gastruloids, morphospace, glycolysis, oxidative phosphorylation, singlecell RNA-seq, machine learning, neuro-mesodermal progenitors, somitogenesis, organoids

2023 November

Fluctuating temperatures exacerbate the effects of nutritional stress during development in Drosophila melanogaster

Brooke Zanco, Juliano Morimoto, Fiona Cockerell, Christen Mirth, Carla M. Sgrò

https://www.biorxiv.org/content/10.1101/2023.11.28.569099v1

Evolutionary biology, Temperature, Nutrition, Local Adaptation, Diel Cycles, Climate Change, Development, Drosophila melanogaster

Modelling variability and heterogeneity of EMT scenarios highlights nuclear positioning and protrusions as main drivers of extrusion

Steffen Plunder, Cathy Danesin, Bruno Glise, Marina A. Ferreira, Sara Merino Aceituno, Eric Theveneau

https://www.biorxiv.org/content/10.1101/2023.11.17.567510v1

Developmental biology, EMT, nuclear positioning

Cadherins modulate the self-organizing potential of gastruloids

Alexandre Mayran, Dominique Kolly, Lucille Lopez-Delisle, Yuliia Romaniuk, Maxine Leonardi, Anne-Catherine Cossy, Theo Lacroix, Ana Rita Amândio, Pierre Osteil, Denis Duboule

https://www.biorxiv.org/content/10.1101/2023.11.22.568291v2

Developmental biology, Self-organization, EMT, Pluripotency, Gastruloids, Snai1, Chromatin, Somitogenesis

Planar polarized force propagation integrates cell behavior with tissue shaping during convergent extension

Shinuo Weng, John B. Wallingford

https://www.biorxiv.org/content/10.1101/2022.11.08.515701v2

Developmental biology, planar cell polarity, convergent extension movements, force inference, chick embryos

New tools reveal PCP-dependent polarized mechanics in the cortex and cytoplasm of single cells during convergent extension

Shinuo Weng, Caitlin C. Devitt, Bill M. Nyaoga, Anna E. Havnen, José Alvarado, John B. Wallingford

https://www.biorxiv.org/content/10.1101/2023.11.07.566066v1

Developmental biology, planar cell polarity, convergent extension movements, force inference

Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in Drosophila

Jonathan A. Jackson, Marlis Denk-Lobnig, Katherine A. Kitzinger, Adam C. Martin

https://www.biorxiv.org/content/10.1101/2023.11.06.565883v1

Cell biology, RhoA, actomyosin cortex, excitability, development, Drosophila egg chamber, Drosophila embryo

Hsp90 shapes adaptation by controlling the fitness consequences of regulatory variation

Christopher Jakobson, José Aguilar-Rodríguez, Daniel F Jarosz

https://www.biorxiv.org/content/10.1101/2023.10.30.564848v1

Evolutionary biology, Hsp90, genetic variability, evolutionary selection, adaptation, Saccharomyces cerevisiae

2023 October

Continuously fluctuating selection reveals extreme granularity and parallelism of adaptive tracking

M.C. Bitter, S. Berardi, H. Oken, A. Huynh, P. Schmidt, D.A. Petrov

https://www.biorxiv.org/content/10.1101/2023.10.16.562586v1

Evolutionary biology, adaptative tracking, standing genetic variation, common garden experiments, Drosophila

Genomic Diversity Illuminates the Environmental Adaptation of Drosophila suzukii

Siyuan Feng, Samuel P. DeGrey, Christelle Guédot, Sean D. Schoville, John E. Pool

https://www.biorxiv.org/content/10.1101/2023.07.03.547576v2

Evolutionary biology, environmental adaptation, genotype-environment association, invasion genomics, Drosophila suzukii

Cut it out: Out-of-plane stresses in cell sheet folding of Volvox embryos

Pierre A. Haas, Stephanie S. M. H. Höhn

https://www.biorxiv.org/content/10.1101/2023.10.17.562736v1

Developmental biology, cell sheet folding, tissue elasticity, volvox, non-model species

Tropical high-altitude insects show limited capacity to handle high temperatures

Harshad Vijay Mayekar, Pooran Singh Solanki, Homica Arya, Rajaguru Aradhya, Prashanth Suravajhala, Volker Loeschcke, Subhash Rajpurohit

https://www.biorxiv.org/content/10.1101/2022.09.10.507406v2

Evolutionary biology, Heat, Climate change, Rapid adaptation, High altitudes, Drosophila

Scale-independent topological interactions drive the first fate decision in the Drosophila embryo

Woonyung Hur, Arghyadip Mukherjee, Luke Hayden, Ziqi Lu, Anna Chao, Noah P. Mitchell, Sebastian J. Streichan, Massimo Vergassola, Stefano Di Talia

https://www.biorxiv.org/content/10.1101/2023.10.11.561879v1

Developmental biology, Embryogenesis, Spindle orientation, Nuclear fate, Microtubule structures, Cell fate determination, Drosophila

Vinculin Antagonizes Branched Actin in Controlling Membrane Protrusion, Cell Migration and Cell Cycle Progression

John James, Artem I. Fokin, Dmitry Y. Guschin, Hong Wang, Anna Polesskaya, Svetlana N. Rubtsova, Christophe Le Clainche, Pascal Silberzan, Alexis M. Gautreau, Stéphane Romero

https://www.biorxiv.org/content/10.1101/2023.10.09.561480v2

Cell biology, Vinculin, Mechanotransducer, Cell adhesions, Arp2/3, Actin networks, Migration, Cell-cell junctions

Visualisation of gene expression within the context of tissues: an X-ray computed tomography-based multimodal approach

Kristaps Kairiss, Natalia Sokolova, Lucie Zilova, Christina Schlagheck, Robert Reinhardt, Tilo Baumbach, Tomas Farago, Thomas van de Kamp, Joachim Wittbrodt, Venera Weinhardt

https://www.biorxiv.org/content/10.1101/2023.10.09.561491v1

Developmental biology, multimodal labelling, X-ray computed-tomography, light sheet microscopy, in situ hybridisation, immunofluorescence, rice fish (medaka), organoids

2023 September

Myocardin-related transcription factors regulate morphogenetic events in vertebrate embryos by controlling F-actin organization and apical constriction

Keiji Itoh, Olga Ossipova, Miho Matsuda, Sergei Y Sokol

https://www.biorxiv.org/content/10.1101/2023.09.27.559818v1

Developmental biology, Mrtf, serum response factor, morphogenesis, gastrulation, megakaryoblastic leukemia, Mkl, F-actin, Xenopus embryo, apical constriction, blastopore, neural tube closure, tricellular junctions

Notch signalling plays a critical role in patterning the ventral mesoderm during early embryogenesis in Drosophila melanogaster

Marvel Megaly, Gregory Foran, Arsala Ali, Anel Turgambayeva, Ryan D. Hallam, Aleksandar Necakov

https://www.biorxiv.org/content/10.1101/2023.09.27.558900v1

Developmental biology, Notch signalling, Drosophila, mesoderm, morphogenesis, dorso-ventral patterning

Embryogenesis in myrmicine ants combines features of short and long germ-band modes of development

Chi-Chun Fang, Arjuna Rajakumar, Andrew Kenny, Ulrich G. Mueller, Ehab Abouheif, David Stein

https://www.biorxiv.org/content/10.1101/2023.09.19.557849v1

Developmental biology, morphogenesis, embryogenesis, segmental patterning, development in non-model organisms, ant species, Hymenoptera

Sensitivity of the timing of Drosophila pupal wing morphogenesis to external perturbations

Romina Piscitello-Gómez, Ali Mahmoud, Natalie A Dye, Suzanne Eaton

https://www.biorxiv.org/content/10.1101/2023.09.22.558969v1

Developmental biology, morphogenesis, Drosophila, pupal wing

Strong environmental memory revealed by experimental evolution in static and fluctuating environments

Clare I. Abreu, Shaili Mathur, Dmitri A. Petrov

https://www.biorxiv.org/content/10.1101/2023.09.14.557739v2

Evolutionary biology, laboratory evolution, barcoded yeast lineages, non-additive effects, environmental memory

Genetic basis of variation in thermal developmental plasticity for Drosophila melanogaster body pigmentation

E Lafuente, D Duneau, P Beldade

https://www.biorxiv.org/content/10.1101/2023.09.03.556093v1

Evolutionary biology, developmental plasticity; thermal melanism; insect coloration; Genome-Wide Association Study (GWAS); Drosophila Genetic Reference Panel (DGRP); seasonal variation

2023 August

Immigration delays but does not prevent adaptation following environmental change: experimental evidence

Lily F. Durkee, Laure Olazcuaga, Brett A. Melbourne, Ruth A. Hufbauer

https://www.biorxiv.org/content/10.1101/2023.08.31.555763v2

Evolutionary biology, natural selection, evolutionary rescue, dispersal, Tribolium castaneum, gene flow, translocation

Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension

Jianbo Wang, Chenbei Chang, Hwa-seon Seo, Deli Yu, Ivan Popov, Jiahui Tao, Allyson Angermeier, Bingdong Sha, Jeffrey D. Axelrod

https://www.biorxiv.org/content/10.1101/2023.08.29.555374v2

Developmental biology, convergent extension, planar cell polarity, non-canonical wnt signalling, Xenopus embryos

Morphogen gradients can convey position and time in growing tissues

Roman Vetter, Dagmar Iber

https://www.biorxiv.org/content/10.1101/2023.08.28.555133v2

Developmental biology, tissue patterning, morphogen gradient, time, opposing gradients, neural tube, Sonic hedgehog

Morphodynamics of human early brain organoid development

Akanksha Jain, Gilles Gut, Fátima Sanchis-Calleja, Ryoko Okamoto, Simon Streib, Zhisong He, Fides Zenk, Malgorzata Santel, Makiko Seimiya, René Holtackers, Sophie Martina Johanna Jansen, J. Gray Camp, Barbara Treutlein

https://www.biorxiv.org/content/10.1101/2023.08.21.553827v1

Developmental biology, brain organoid, light sheet microscopy, single-cell transcriptome, mechanosensing

Nucleotide sharing through gap junctions buffers replication stress

Benjamin Boumard, Gwenn Le Meur, Tania Maalouf, Marwa El-Hajj, Reinhard Bauer, Allison J. Bardin

https://www.biorxiv.org/content/10.1101/2023.08.15.553366v1

Developmental biology, gap junctions, metabolism, replication stress, stem cells

Successful regeneration of the adult zebrafish retina is dependent on inflammatory signaling

Oliver Bludau, Anke Weber, Viktoria Bosak, Veronika Kuscha, Kristin Dietrich, Stefan Hans, Michael Brand

https://www.biorxiv.org/content/10.1101/2023.08.11.552956v2

Developmental biology, immune suppression, M-CSF, microglia, Müller glia, NF-κB  pathway, retina regeneration, zebrafish

Conserved and novel enhancers regulate expression of Aedes aegypti single-minded in the embryonic ventral midline

Isabella Schember, William Reid, Marc S. Halfon

https://www.biorxiv.org/content/10.1101/2023.08.01.551414v2

Evolutionary biology, enhancer evolution, single minded, nervous system master regulator, embryo development, Aedes aegypti, Drosophila melanogaster,

2023 July

Global decoupling of cell differentiation from cell division in early embryo development

Kalki Kukreja, Nikit Patel, Sean G Megason, Allon M Klein

https://www.biorxiv.org/content/10.1101/2023.07.29.551123v1

Developmental biology, cell division, cell differentiation, embryo development, single-cell RNAseq, zebrafish

Cell division angle regulates the tissue mechanics and tunes the amount of cerebellar folding

Amber G. Cook, Taylor V. Bishop, Hannah R. Crowe, Daniel Stevens, Lauren Reine, Alexandra L Joyner, Andrew K Lawton

https://www.biorxiv.org/content/10.1101/2023.07.21.549165v1

Developmental biology, cerebellum, brain folding, cell division angle, tissue mechanics, mouse models

Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

Nadia M.E. Ayad, Johnathon N. Lakins, Ajinkya Ghagre, Allen J. Ehrlicher, Valerie M. Weaver

https://www.biorxiv.org/content/10.1101/2023.07.14.549074v1

Developmental biology, gastrulation, mechanical forces, β-catenin, mesoderm specification, Wnt signaling, human embryonic stem cells, cytoskeletal tension, mechanotransduction, gastruloids, traction force microscopy (TFM)

Naturally segregating genetic variants contribute to thermal tolerance in a D. melanogaster model system

Patricka A. Williams-Simon, Camille Oster, Jordyn A. Moaton, Ronel Ghidey, Enoch Ng’oma, Kevin M. Middleton, Troy Zars, Elizabeth G. King

https://www.biorxiv.org/content/10.1101/2023.07.06.547110v1

Evolutionary biology, QTL, Thermal Tolerance, DSPR, RNA-seq, Gene Expression, RNAi, Complex Traits, Drosophila

2023 May

Distinctive cellular and junctional dynamics independently regulate the rotation and elongation of the internal organ

Mikiko Inaki, Takamasa Higashi, Satoru Okuda, Kenji Matsuno

https://www.biorxiv.org/content/10.1101/2023.05.22.541825v1

Developmental biology, chiral cell-sliding, cell-intercalation, gut tube rotation, left-right asymmetry, Drosophila

Apical-driven cell sorting optimised for tissue geometry ensures robust patterning

https://www.biorxiv.org/content/10.1101/2023.05.16.540918v1

Developmental biology, fate segregation, cell mechanics, cell sorting, cell migration, apical polarity, extracellular matrix, tissue geometry, embryo patterning, robustness, morphogenesis

Inverse blebs operate as hydraulic pumps during mouse blastocyst formation

Markus F. Schliffka, Julien G. Dumortier, Diane Pelzer, Arghyadip Mukherjee, Jean-Léon Maître

https://www.biorxiv.org/content/10.1101/2023.05.03.539105v1

Developmental biology, lumen formation, fluid pressure, cell adhesion, mouse embryos

2023 April

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

Anna R. Yeh, Gregory J. Hoeprich, Bruce L. Goode, Adam C. Martin

https://www.biorxiv.org/content/10.1101/2023.04.17.537198v1

Developmental biology, syncytial divisions, F-actin regulation, Drosophila

2023 March

Mitochondrial morphology dynamics and ROS regulate apical polarity and differentiation in Drosophila follicle cells

Bhavin Uttekar, Darshika Tomer, Richa Rikhy

https://www.biorxiv.org/content/10.1101/2023.03.10.532033v1

Developmental biology, epithelial polarity, mitochondria, ROS, aPKC, Drp1, Opa1, Drosophila