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TAGC 2020

Preprints recently presented at the virtual Allied Genetics Conference, April 22-26, 2020. #TAGC20

List by Maiko Kitaoka, Madhuja Samaddar, Miguel V. Almeida, Sejal Davla, Jennifer Ann Black, Dey Lab

Preprints:

Polyploidy in the adult Drosophila brain

Shyama Nandakumar, Olga Grushko, Laura A. Buttitta

https://www.biorxiv.org/content/10.1101/852723v2

Dense encoding of developmental regulatory information may constrain evolvability

Timothy Fuqua, Jeff Jordan, Maria Elize van Breugel, Aliaksandr Halavatyi, Christian Tischer, Peter Polidoro, Namiko Abe, Albert Tsai, Richard S. Mann, David L. Stern, Justin Crocker

https://www.biorxiv.org/content/10.1101/2020.04.17.046052v1

Topology-driven analysis of protein-protein interaction networks detects functional genetic modules regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G. Extavour

https://www.biorxiv.org/content/10.1101/852897v1

The transcription regulatory code of a maize leaf

Xiaoyu Tu, María Katherine Mejía-Guerra, Jose A. Valdes Franco, David Tzeng, Po-Yu Chu, Xiuru Dai, Pinghua Li, Edward S Buckler, Silin Zhong

https://www.biorxiv.org/content/10.1101/2020.01.07.898056v2

longfin causes cis-ectopic expression of the kcnh2a ether-a-go-go K+ channel to autonomously prolong fin outgrowth

Scott Stewart, Heather K. Le Bleu, Gabriel A. Yette, Astra L. Henner, Joshua A. Braunstein, Kryn Stankunas

https://www.biorxiv.org/content/10.1101/790329v1

Skeletal geometry and niche transitions restore organ size and shape during zebrafish fin regeneration

Scott Stewart, Gabriel A. Yette, Heather K. Le Bleu, Astra L. Henner, Joshua A. Braunstein, Jad W. Chehab, Michael J. Harms, Kryn Stankunas

https://www.biorxiv.org/content/10.1101/606970v3

Hmx3a does not require its homeodomain for its essential functions in spinal cord, ear and lateral line development

Samantha J. England, Gustavo A. Cerda, Angelica Kowalchuk, Taylor Sorice, Ginny Grieb, Katharine E. Lewis

https://www.biorxiv.org/content/10.1101/2020.01.23.917468v2.full

Visualizing the metazoan proliferation-differentiation decision in vivo

Abraham Q. Kohrman, Rebecca C. Adikes, Jayson J. Smith, Michael A. Q. Martinez, Taylor N. Medwig-Kinney, Nicholas J. Palmisano, Maria D. Sallee, Ononnah B. Ahmed, Nicholas Weeks, Nuri Kim, Simeiyun Liu, Wan Zhang, Ariel M. Pani, David Q. Matus

https://www.biorxiv.org/content/10.1101/2019.12.18.881888v1

Stem cell differentiation trajectories in Hydra resolved at single-cell resolution

Stefan Siebert, Jeffrey A. Farrell, Jack F. Cazet, Yashodara L. Abeykoon, Abby S. Primack, Christine E. Schnitzler, Celina E. Juliano

https://www.biorxiv.org/content/10.1101/460154v1

Emergence of neuronal diversity during vertebrate brain development

Bushra Raj, Jeffrey A. Farrell, Aaron McKenna, Jessica L. Leslie, Alexander F. Schier

https://www.biorxiv.org/content/10.1101/839860v1

The Vertebrate Codex Gene Breaking Protein Trap Library For Genomic Discovery and Disease Modeling Applications

Noriko Ichino, MaKayla Serres, Rhianna Urban, Mark Urban, Kyle Schaefbauer, Lauren Greif, Gaurav K. Varshney, Kimberly J. Skuster, Melissa McNulty, Camden Daby, Ying Wang, Hsin-kai Liao, Suzan El-Rass, Yonghe Ding, Weibin Liu, Lisa A. Schimmenti, Sridhar Sivasubbu, Darius Balciunas, Matthias Hammerschmidt, Steven A. Farber, Xiao-Yan Wen, Xiaolei Xu, Maura McGrail, Jeffrey J. Essner, Shawn Burgess, Karl J. Clark, Stephen C. Ekker

https://www.biorxiv.org/content/10.1101/630236v1

GCNA interacts with Spartan and Topoisomerase II to regulate genome stability

Gregory M. Davis, Gregoriy A. Dokshin, Ashley D. Sawle, Matthew D. Eldridge, Katherine A. Romer, Taylin E. Gourley, Luke W. Molesworth, Hannah R. Tatnell, Ahmet R. Ozturk, Dirk G. de Rooij, Gregory J. Hannon, David C. Page, Craig C. Mello, Michelle A. Carmell

https://www.biorxiv.org/content/10.1101/570200v1

mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage

Dylan M. Parker, Lindsay P. Winkenbach, Samuel P. Boyson, Matthew N. Saxton, Camryn Daidone, Zainab A. Al-Mazaydeh, Marc T. Nishimura, Florian Mueller, Erin Osborne Nishimura

https://www.biorxiv.org/content/10.1101/2020.01.09.900498v1

A developmental gene regulatory network for invasive differentiation of the C. elegans anchor cell

Taylor N. Medwig-Kinney, Jayson J. Smith, Nicholas J. Palmisano, Sujata Tank, Wan Zhang, David Q. Matus

https://www.biorxiv.org/content/10.1101/691337v3

Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo

Aniek van der Vaart, Molly Godfrey, Vincent Portegijs, Sander van den Heuvel

https://www.biorxiv.org/content/10.1101/636720v1

CeMbio - The C. elegans microbiome resource

Philipp Dirksen, Adrien Assié, Johannes Zimmermann, Fan Zhang, Adina-Malin Tietje, Sarah Arnaud Marsh, Marie-Anne Félix, Michael Shapira, Christoph Kaleta, Hinrich Schulenburg, Buck S. Samuel

https://www.biorxiv.org/content/10.1101/2020.04.22.055426v1

Regenerative capacity in Drosophila imaginal discs is controlled by damage-responsive, maturity-silenced enhancers

Robin E. Harris, Michael J. Stinchfield, Spencer L. Nystrom, Daniel J. McKay, Iswar K. Hariharan

https://www.biorxiv.org/content/10.1101/820605v2

Delineation of the SUMO-Modified Proteome Reveals Regulatory Functions Throughout Meiosis

Nikhil R Bhagwat, Shannon Owens, Masaru Ito, Jay Boinapalli, Philip Poa, Alexander Ditzel, Srujan Kopparapu, Meghan Mahalawat, Owen R Davies, Sean R Collins, Jeffrey Johnson, Nevan J Krogan, Neil Hunter

https://www.biorxiv.org/content/10.1101/828442v1

Shadow enhancers suppress input transcription factor noise through distinct regulatory logic

Rachel Waymack, Alvaro Fletcher, German Enciso, Zeba Wunderlich

https://www.biorxiv.org/content/10.1101/778092v1

Reorganization of 3D genome structure in the Drosophila melanogaster species group

Nicole S. Torosin, Aparna Anand, Tirupathi Rao Golla, Weihuan Cao, Christopher E. Ellison

https://www.biorxiv.org/content/10.1101/2020.04.09.033753v1

Neuropeptide VF neurons promote sleep via the serotonergic raphe

Daniel A. Lee, Grigorios Oikonomou, Tasha Cammidge, Young Hong, David A. Prober

https://www.biorxiv.org/content/10.1101/2019.12.27.889402v1

ER stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress

Nurulain Ho, Haoxi Wu, Jiaming Xu, Jhee Hong Koh, Wei Sheng Yap, Wilson Wen Bin Goh, Shu Chen Chong, Stefan Taubert, Guillaume Thibault

https://www.biorxiv.org/content/10.1101/774133v1

Translational control of methionine and serine metabolic pathways underpin the paralog-specific phenotypes of Rpl22 ribosomal protein mutants in cell division and replicative longevity

Nairita Maitra, Chong He, Heidi M. Blank, Mitsuhiro Tsuchiya, Birgit Schilling, Matt Kaeberlein, Rodolfo Aramayo, Brian K. Kennedy, Michael Polymenis

https://www.biorxiv.org/content/10.1101/2020.02.05.935726v1

Unexpected variability of allelic imbalance estimates from RNA sequencing

Asia Mendelevich, Svetlana Vinogradova, Saumya Gupta, Andrey A. Mironov, Shamil Sunyaev, Alexander A. Gimelbrant

https://www.biorxiv.org/content/10.1101/2020.02.18.948323v2

Mechanism of monoallelic expression and allelic rheostat role of DNA methylation

Saumya Gupta, Denis L. Lafontaine, Sebastien Vigneau, Svetlana Vinogradova, Asia Mendelevich, Kyomi J. Igarashi, Andrew Bortvin, Clara F. Alves-Pereira, Kendell Clement, Luca Pinello, Andreas Gnirke, Henry Long, Alexander Gusev, Anwesha Nag, Alexander A. Gimelbrant

https://www.biorxiv.org/content/10.1101/2020.02.20.954834v1

Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish

Daniel L. Powell, Mateo Garcia, Mackenzie Keegan, Patrick Reilly, Kang Du, Alejandra P. Díaz-Loyo, Shreya Banerjee, Danielle Blakkan, David Reich, Peter Andolfatto, Gil Rosenthal, Manfred Schartl, Molly Schumer

https://www.biorxiv.org/content/10.1101/2019.12.12.874586v1

Learning the properties of adaptive regions with functional data analysis

Mehreen R. Mughal, Hillary Koch, Jinguo Huang, Francesca Chiaromonte, Michael DeGiorgio

https://www.biorxiv.org/content/10.1101/834010v1

Assembly of a young vertebrate Y chromosome reveals convergent signatures of sex chromosome evolution

Catherine L. Peichel, Shaugnessy R. McCann, Joseph A. Ross, Alice F. S. Naftaly, James R. Urton, Jennifer N. Cech, Jane Grimwood, Jeremy Schmutz, Richard M. Myers, David M. Kingsley, Michael A. White

https://www.biorxiv.org/content/10.1101/2019.12.12.874701v2

Model-based assessments of differential introgression and linked natural selection during divergence and speciation

Arun Sethuraman, Vitor Sousa, Jody Hey

https://www.biorxiv.org/content/10.1101/786038v1

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins

Chanjae Lee, Rachael M. Cox, Ophelia Papoulas, Amjad Horani, Kevin Drew, Caitlin C. Devitt, Steven L. Brody, Edward M. Marcotte, John B. Wallingford

https://www.biorxiv.org/content/10.1101/2020.04.21.052837v1

A systematic, label-free method for identifying RNA-associated proteins in vivo provides insights into vertebrate ciliary beating

Kevin Drew, Chanjae Lee, Rachael M. Cox, Vy Dang, Caitlin C. Devitt, Ophelia Papoulas, Ryan L. Huizar, Edward M. Marcotte, John B. Wallingford

https://www.biorxiv.org/content/10.1101/2020.02.26.966754v2

The interaction of crossover formation and the dynamic architecture of the synaptonemal complex during meiosis

Simone Köhler, Michal Wojcik, Ke Xu, Abby F. Dernburg

https://www.biorxiv.org/content/10.1101/2020.02.16.947804v1

Patched regulates lipid homeostasis by controlling cellular cholesterol levels

Carla E. Cadena del Castillo, J. Thomas Hannich, Andres Kaech, Hirohisa Chiyoda, Masamitsu Fukuyama, Nils J. Færgeman, Howard Riezman, Anne Spang

https://www.biorxiv.org/content/10.1101/816256v1

Most cancers carry a substantial deleterious load due to Hill-Robertson interference

Susanne Tilk, Christina Curtis, Dmitri A Petrov, Christopher D McFarland

https://www.biorxiv.org/content/10.1101/764340v2

Learning the properties of adaptive regions with functional data analysis

Mehreen R. Mughal, Hillary Koch, Jinguo Huang, Francesca Chiaromonte, Michael DeGiorgio

https://www.biorxiv.org/content/10.1101/834010v1

Population genetics of the coral Acropora millepora: Towards a genomic predictor of bleaching

Zachary L. Fuller, Veronique J.L. Mocellin, Luke Morris, Neal Cantin, Jihanne Shepherd, Luke Sarre, Julie Peng, Yi Liao, Joseph Pickrell, Peter Andolfatto, Mikhail Matz, Line K. Bay, Molly Przeworski

https://www.biorxiv.org/content/10.1101/867754v1

Recombination, variance in genetic relatedness, and selection against introgressed DNA

Carl Veller, Nathaniel B. Edelman, Pavitra Muralidhar, Martin A. Nowak

https://www.biorxiv.org/content/10.1101/846147v1

Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping

Kerry A Geiler-Samerotte, Shuang Li, Charalampos Lazaris, Austin Taylor, Naomi Ziv, Chelsea Ramjeawan, Annalise B Paaby, Mark L Siegal

https://www.biorxiv.org/content/10.1101/700716v1.full

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EMBL Conference: From functional genomics to systems biology

Preprints presented at the virtual EMBL conference "from functional genomics and systems biology", 16-19 November 2020

 



List by Jesus Victorino

TAGC 2020

Preprints recently presented at the virtual Allied Genetics Conference, April 22-26, 2020. #TAGC20

 



List by Maiko Kitaoka et al.

ECFG15 – Fungal biology

Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome

 



List by Hiral Shah

Autophagy

Preprints on autophagy and lysosomal degradation and its role in neurodegeneration and disease. Includes molecular mechanisms, upstream signalling and regulation as well as studies on pharmaceutical interventions to upregulate the process.

 



List by Sandra Malmgren Hill

Zebrafish immunology

A compilation of cutting-edge research that uses the zebrafish as a model system to elucidate novel immunological mechanisms in health and disease.

 



List by Shikha Nayar

Also in the genomics category:

End-of-year preprints – the genetics & genomics edition

In this community-driven preList, a group of preLighters, with expertise in different areas of genetics and genomics have worked together to create this preprint reading list. Categories include: 1) genomics 2) bioinformatics 3) gene regulation 4) epigenetics

 



List by Chee Kiang Ewe et al.

BSCB-Biochemical Society 2024 Cell Migration meeting

This preList features preprints that were discussed and presented during the BSCB-Biochemical Society 2024 Cell Migration meeting in Birmingham, UK in April 2024. Kindly put together by Sara Morais da Silva, Reviews Editor at Journal of Cell Science.

 



List by Reinier Prosee

9th International Symposium on the Biology of Vertebrate Sex Determination

This preList contains preprints discussed during the 9th International Symposium on the Biology of Vertebrate Sex Determination. This conference was held in Kona, Hawaii from April 17th to 21st 2023.

 



List by Martin Estermann

Semmelweis Symposium 2022: 40th anniversary of international medical education at Semmelweis University

This preList contains preprints discussed during the 'Semmelweis Symposium 2022' (7-9 November), organised around the 40th anniversary of international medical education at Semmelweis University covering a wide range of topics.

 



List by Nándor Lipták

20th “Genetics Workshops in Hungary”, Szeged (25th, September)

In this annual conference, Hungarian geneticists, biochemists and biotechnologists presented their works. Link: http://group.szbk.u-szeged.hu/minikonf/archive/prg2021.pdf

 



List by Nándor Lipták

EMBL Conference: From functional genomics to systems biology

Preprints presented at the virtual EMBL conference "from functional genomics and systems biology", 16-19 November 2020

 



List by Jesus Victorino

TAGC 2020

Preprints recently presented at the virtual Allied Genetics Conference, April 22-26, 2020. #TAGC20

 



List by Maiko Kitaoka et al.

Also in the cell biology category:

Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer

Jasmin Kaivola, Karolina Punovuori, Megan R. Chastney, et al.

Selected by 19 December 2024

Teodora Piskova

Cancer Biology

Germplasm stability in zebrafish requires maternal Tdrd6a and Tdrd6c

Alessandro Consorte, Yasmin El Sherif, Fridolin Kielisch, et al.

Selected by 13 December 2024

Justin Gutkowski

Developmental Biology

Leukocytes use endothelial membrane tunnels to extravasate the vasculature

Werner J. van der Meer, Abraham C.I. van Steen, Eike Mahlandt, et al.

Selected by 08 December 2024

Felipe Del Valle Batalla

Cell Biology

Also in the developmental biology category:

Germplasm stability in zebrafish requires maternal Tdrd6a and Tdrd6c

Alessandro Consorte, Yasmin El Sherif, Fridolin Kielisch, et al.

Selected by 13 December 2024

Justin Gutkowski

Developmental Biology

Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis

Joshua Hawley, Robert Lea, Veronica Biga, et al.

Selected by 15 November 2024

Ankita Walvekar

Developmental Biology

Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation

Marianne Basso, Alexia Mahuzier, Syed Kaabir Ali, et al.

Selected by 30 October 2024

Ryan Harrison

Developmental Biology

Also in the evolutionary biology category:

Geometric analysis of airway trees shows that lung anatomy evolved to enable explosive ventilation and prevent barotrauma in cetaceans

Robert L. Cieri, Merryn H. Tawhai, Marina Piscitelli-Doshkov, et al.

Selected by 26 November 2024

Sarah Young-Veenstra

Evolutionary Biology

Enhancer-driven cell type comparison reveals similarities between the mammalian and bird pallium

Nikolai Hecker , Niklas Kempynck , David Mauduit, et al.

Selected by 02 July 2024

Rodrigo Senovilla-Ganzo

Bioinformatics

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

Selected by 24 June 2024

Girish Kale, Jennifer Ann Black

Developmental Biology

Also in the genetics category:

Intracellular diffusion in the cytoplasm increases with cell size in fission yeast

Catherine Tan, Michael C. Lanz, Matthew Swaffer, et al.

Selected by 18 October 2024

Leeba Ann Chacko, Sameer Thukral

Cell Biology

HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

Estefania Sanchez-Vasquez, Marianne E. Bronner, Magdalena Zernicka-Goetz

Selected by 11 October 2024

Anchel De Jaime Soguero

Developmental Biology

Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA

Brett T. Wisniewski, Laura L. Lackner

Selected by 30 August 2024

Leeba Ann Chacko

Cell Biology

Also in the genomics category:

A fine kinetic balance of interactions directs transcription factor hubs to genes

Apratim Mukherjee, Samantha Fallacaro, Puttachai Ratchasanmuang, et al.

Selected by 23 July 2024

Deevitha Balasubramanian

Genomics

Enhancer-driven cell type comparison reveals similarities between the mammalian and bird pallium

Nikolai Hecker , Niklas Kempynck , David Mauduit, et al.

Selected by 02 July 2024

Rodrigo Senovilla-Ganzo

Bioinformatics

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

Selected by 24 June 2024

Girish Kale, Jennifer Ann Black

Developmental Biology

Also in the physiology category:

Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates

Karen A Lindquist, Jennifer Mecklenburg, Anahit H. Hovhannisyan, et al.

Selected by 04 December 2024

Vanessa Ehlers

Neuroscience

Geometric analysis of airway trees shows that lung anatomy evolved to enable explosive ventilation and prevent barotrauma in cetaceans

Robert L. Cieri, Merryn H. Tawhai, Marina Piscitelli-Doshkov, et al.

Selected by 26 November 2024

Sarah Young-Veenstra

Evolutionary Biology

Precision Farming in Aquaculture: Use of a non-invasive, AI-powered real-time automated behavioural monitoring approach to predict gill health and improve welfare in Atlantic salmon (Salmo salar) aquaculture farms

Meredith Burke, Dragana Nikolic, Pieter Fabry, et al.

Selected by 11 September 2024

Jasmine Talevi

Animal Behavior and Cognition
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