April in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics
List by Vibha SINGH, Matthew Davies, Chee Kiang Ewe, Sristilekha Nath, Felipe Del Valle Batalla, Girish Kale
Preprints:
Biochemistry/metabolism
An intercellular metabolic relay for brain sparing in Drosophila
https://www.biorxiv.org/content/10.1101/2025.04.02.645514v1
This preprint identifies the mechanism that underlies sparing of the central nervous system under nutrient-deprived conditions. The authors show that this hinges on metabolism of circulating glutamine to fuel proliferation of neural stem cells.
Picked by: Matthew Davies
From Franchet et al. (2025). This image is made available under a CC-BY 4.0 International license.
Cell cycle and division
A Morpho-Proteomic Atlas of Mitosis at Sub-Minute Resolution
https://www.biorxiv.org/content/10.1101/2025.04.09.647158v1.abstract?%3Fcollection=
This preprint establishes a strong link between morphology and proteome during various phases of the cell cycle, using high-throughput techniques. The authors have also developed an online resource, called mito-Omix, to browse through their data on morphological and proteomic changes.
Picked by: Girish Kale
Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tension via NuMA localisation
https://www.biorxiv.org/content/10.1101/2024.10.17.617436v3.abstract?%3Fcollection=
This work focuses on a regulator of mitotic spindle organization called Nuclear Mitotic Apparatus (NuMA), which the authors show to be responsive to external mechanical stimuli. This preprint adds important details to our understanding of what regulates the in-plane divisions in epithelial tissues, even though the apicobasal axis is the long axis of the cell. The authors distinguish the role of cell elongation vs. mechanical forces in the plane of the epithelium to orient the spindle.
Picked by: Girish Kale
Wnt10b signaling regulates replication stress-induced chromosomal instability in human cancer
https://www.biorxiv.org/content/10.1101/2025.04.23.650265v2.abstract?%3Fcollection=
Chromosomal missegregation and aneuploidy during cell division are hallmarks of cancerous cells. In this preprint, the authors show that Wnt signalling, specifically that initiated by Wnt10b, is involved in regulating cell division during the S-phase. During DNA replication stress, Wnt10b signalling prevents premature microtubule dynamics, reducing replication-induced chromosomal breaks.
Picked by: Girish Kale
Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis
https://www.biorxiv.org/content/10.1101/2025.04.04.647290v1.abstract?%3Fcollection=
This preprint focuses on microtubules made of distinct alpha-tubulin isotypes, and how they regulate binding of distinct motor proteins and Microtubule Associated Proteins (MAPs). Their experiments in budding yeast provide insights into spindle morphogenesis, as the combined activity of the two isotypes (Tub1 and 3) is required to build a spindle with normal length.
Picked by: Girish Kale
From Nsamba et al. (2025). This image is made available under a CC-BY-NC-ND 4.0 International license.
Cell organelles and organisation
Spatial activation of Kinesin-1 by Ensconsin shapes microtubule networks via ncMTOCs recruitment
https://www.biorxiv.org/content/10.1101/2025.04.15.648882v1
During oogenesis, early oocytes must become polarised. This study identifies kinesin-1 and ensconsin (MAP7) as components that facilitate recruitment of microtubule organising centres (MTOC) to the cortex to allow polarisation. Kinesin-1/ensconsin-mediated recruitment of MTOC factors may be a mechanism utilised in multiple cell types to establish polarity.
Picked by: Matthew Davies
Mitochondrial fission during mitophagy requires both inner and outer mitofissins
https://www.biorxiv.org/content/10.1101/2025.04.13.648642v1
This work is relevant because it identifies a new outer mitochondrial membrane protein, Mfi2, as a key factor in mitochondrial fission during mitophagy. This finding refines the understanding of the complex mechanisms that ensure selective degradation of damaged mitochondria.
Picked by: Felipe Del Valle Batalla
Curvature-dependent morphological reorganization of the endoplasmic reticulum determines the mode of epithelial migration
https://www.biorxiv.org/content/10.1101/2025.04.22.650137v1.abstract?%3Fcollection=
Endoplasmic Reticulum (ER) exists as sheets and tubules, responding to reorganization of the cytoskeleton. Such reorganization can happen during cell migration and wound healing. The authors show that ER reorganization is an essential component of a cell’s response to physical stimuli, as it regulates the orientation of the mature focal adhesions.
Picked by: Girish Kale
Nuclear envelope budding is a non-canonical mechanism to export large transcripts in muscle cells
https://www.biorxiv.org/content/10.1101/2025.04.18.649598v1.abstract?%3Fcollection=
In this preprint, the authors describe a non-canonical pathway for nuclear export of extremely large transcripts, which can be best described as transport between the inner and outer membranes of the nuclear envelope using an inverse of a neuronal synapse. This is especially required in muscles, as muscles contain several large proteins, including one of the largest proteins, Titin. This pathway is specifically activated as muscle cells differentiate from myoblasts to myotubes, and resembles the pathway used by the Herpesvirus to similarly export itself from the nucleus.
Picked by: Girish Kale
From Zaganelli et al. (2025). This image is made available under a CC-BY 4.0 International license.
Inverted Assembly of the Lens Within Ocular Organoids Reveals Alternate Paths to Ocular Morphogenesis
https://www.biorxiv.org/content/10.1101/2025.04.17.649366v1
This exciting preprint highlights the emergence of lens-like tissues from ocular organoids derived from medaka pluripotent embryonic stem cells, developing in an “outside-in” fashion. Consistent with the in vivo positioning of the lens surrounded by cup-shaped retinal tissue, this finding not only suggests the possibility of an alternative mechanism for lens formation but also demonstrates the potential of organoids as a promising tool to study cell and tissue organization and observe diverse modes of morphogenesis.
Picked by: Sristilekha Nath
Compartmentalization of mRNA and Translation by Desmosomes
https://www.biorxiv.org/content/10.1101/2025.04.17.649424v1.abstract?%3Fcollection=
This preprint focuses on the spatial (re)organization of translation machinery. Desmosomes, which are part of epithelial septate junctions, are shown here to be involved in regulating the translation of cortical mRNAs. This adds another method for the local regulation of translation. The authors show that the transcripts associated with GO terms, cell adhesion and cytoskeleton, were enriched at desmosomes, but only during wound healing, suggesting that these transcripts are maintained as an inactive reservoir to mount a quick response to wounding and to quickly recover epithelial barrier function.
Picked by: Girish Kale
Cell signalling and mechanosensing
Fibroblast growth factor 21 regulates neuromuscular junction innervation through HDAC4 in denervation-induced skeletal muscle atrophy
https://www.biorxiv.org/content/10.1101/2025.02.18.638653v1
The preprint teases apart the role of FGF21, a muscle-secreted paracrine/autocrine signal, that is responsible for muscular atrophy. The secretion is normally triggered in response to a loss of innervation, but an artificial upregulation of FGF21 can also feedback and denervate the skeletal muscles. Downregulating FGF21 can also block denervation and prevent muscular atrophy, suggesting a promising strategy to mitigate skeletal muscle atrophy.
Picked by: Girish Kale
Check out the preLights post covering this preprint: https://prelights.biologists.com/highlights/fibroblast-growth-factor-21-regulates-neuromuscular-junction-innervation-through-hdac4-in-denervation-induced-skeletal-muscle-atrophy/
Actin cytoskeletal remodeling requires the interaction between Solo and LARG in response to substrate stiffness
https://www.biorxiv.org/content/10.1101/2025.04.08.647765v1
Cells remodel their actin cytoskeleton in response to mechanical stimuli. This preprint identifiy Solo (RhoGEF) regulation on PDZ-RhoGEF (PRG) and leukemia-associated RhoGEF (LARG) during mechanical stress and is also required to maintain LARG activity, which in turn is necessary for Solo-induced actin polymerization. This indicates PRG/LARG function cooperatively in Solo-mediated actin regulation in response to substrate stiffness.
Picked by: Vibha Singh
Loofah, a newly characterized adhesion protein, suppresses cell death in long-lived Drosophila hindgut enterocytes
https://www.biorxiv.org/content/10.1101/2025.04.04.647274v1.abstract?%3Fcollection=
This preprint describes a new cell-cell adhesion gene (previously known gene with unknown function) and explores its function in preventing cell death. The authors show that cell-cell adhesion, mediated by this immunoglobulin-family gene, prevents cell death despite pro-apoptotic signals.
Picked by: Girish Kale
Optogenetic control of mechanotransduction based on light-induced homodimerization of talin
https://www.biorxiv.org/content/10.1101/2025.04.17.649301v1
Vibha: This preprint describes a single-component optogenetic system exploiting an light controlled talin homodimerization, overcoming limitations of previous dual-component systems. Optogenetic dimerization of talin boosts adhesion formation and signaling, whereas monomerization interrupts these processes, emphasizing the crucial role of talin dimerization in cell-ECM interactions.
Girish: This preprint describes new tools to tune cell-ECM adhesion via controlling the dimerization of Talin, a component of integrin-based cell-ECM adhesion. Talin naturally exists as a dimer in its active state. Replacing its dimerization domain with a light-inducible dimerization-dissociation fluorescent protein allowed the authors to regulate dimerization directly, controlling the activity of Talin and allowing a thorough characterization of this new tool.
Picked by: Vibha Singh & Girish Kale
From Nishimura et al. (2025). This image is made available under a CC-BY 4.0 International license.
Mechanical Stress dissipation in locally folded epithelia is orchestrated by calcium waves and nuclear tension changes
https://www.biorxiv.org/content/10.1101/2025.04.04.647200v1.abstract?%3Fcollection=
This preprint describes how nuclear deformation and recovery are involved in mechanical stress dissipation, using a mechanism that involves a calcium wave. Preventing the recovery of nuclear shape prevents the dissipation of mechanical stress, indicating a key role of nuclei as cell-intrinsic mechanosensors.
Picked by: Girish Kale
Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting
https://www.biorxiv.org/content/10.1101/2025.04.01.645927v1.abstract?%3Fcollection=
This preprint uses an angiogenesis-on-chip model to elucidate the function of Scribble, an epithelial polarity protein, now in an endothelial context. Their results demonstrate a role for Scribble in directing cortical actomyosin organization for endothelial cell-cell junction integrity.
Picked by: Girish Kale
Elucidating Chiral Myosin-Induced Actin Dynamics: From Single Filament Behavior to Collective Structures
https://www.biorxiv.org/content/10.1101/2025.03.26.645581v2.abstract?%3Fcollection=
This preprint works on a special member of the myosin family of motor proteins. In general, the protein family is rather diverse and is studied quite extensively, yet a subgroup of this family remains underexplored. Here authors focus on myosin-XI, an unconventional motor protein that produces chiral curved motions of actin filaments.
Picked by: Girish Kale
From Haraguchi et al. (2025). This image is made available under a CC-BY 4.0 International license.
A multicellular actin star network underpins epithelial organization and connectivity
https://www.biorxiv.org/content/10.1101/2024.07.26.605277v3.abstract?%3Fcollection=
In this preprint, the authors describe an interesting structure of actin filaments in the form of a six-armed star (one per cell base), which contributes to epithelial organization and packing in intestinal epithelia. The stars interconnect across cells through cell-cell junctions to produce a solid-like organization of the epithelial tissue.
Picked by: Girish Kale
Targeting RhoA activity rejuvenates aged hematopoietic stem cells
https://www.biorxiv.org/content/10.1101/2025.04.23.647902v1
The authors of this preprint discover a previously undescribed mechanotransduction pathway—focused on RhoA— connecting mechanical stress to epigenetic aging in hematopoietic stem cells (HSCs). This proposes that pharmacologic targeting RhoA could be a potential therapeutic strategy to rejuvenate aged stem cells and a treatment for age-associated diseases.
Picked by: Vibha Singh
An optogenetic toolkit for robust activation of FGF, BMP, & Nodal signaling in zebrafish
https://www.biorxiv.org/content/10.1101/2025.04.17.649426v1.abstract?%3Fcollection=
This preprint describes optogenetic tools to activate core cellular pathways in a developmental context. The tools described can activate FGF, Nodal, and BMP signaling pathways, with spatiotemporal specificity. The authors exploit the dimerization of the LOV domain to activate these pathways, as a common theme between these pathways is the dimerization of their signalling components. The authors claim that such an optogenetic strategy can be a more general one, and could likely be implemented in various signaling contexts that involve such dimerization.
Picked by: Girish Kale
FilaBuster: A Strategy for Rapid, Specific, and Spatiotemporally Controlled Intermediate Filament Disassembly
https://www.biorxiv.org/content/10.1101/2025.04.20.649718v1.abstract?%3Fcollection=
This study describes a new set of tools to rapidly disassemble intermediate filaments with high sub-cellular specificity. Even though the strategy requires multiple components, the authors’ detailed characterization of the tool, with various permutations of conditions, should be helpful for anyone who wishes to implement it.
Picked by: Girish Kale
Genetics and epigenetics
tRNA-derived RNA processing in sperm transmits non-genetically inherited phenotypes to offspring in C. elegans
https://www.biorxiv.org/content/10.1101/2025.04.14.648817v1
This great paper showed that in C. elegans, tRNA fragments in sperm can carry epigenetic information across generations, as observed in mammals.
Picked by: Ethan Ewe
From Galambos et al. (2025). This image is made available under a CC-BY-NC-ND 4.0 International license.
Embryo-scale single-cell chemical transcriptomics reveals dependencies between cell types and signaling pathways
https://www.biorxiv.org/content/10.1101/2025.04.03.646423v1.abstract?%3Fcollection=
This preprint presents single-cell RNAseq data after inhibiting all seven major signalling pathways using pharmacological inhibitors. Such analysis would allow us to better understand the dependencies between cell fate specification and various signalling pathways.
Picked by: Girish Kale
Hyperosmotic Stress of HL-60/S4 Cells: Gene Set Enrichment Analysis and Microscopic Changes
https://www.biorxiv.org/content/10.1101/2025.04.22.649232v1
The preprint provides a transcriptomic dataset of genes differentially regulated by hyperosmotic stress. This is a useful source for groups studying the effects of osmotic stress eg. cytosolic viscosity modulation.
Picked by: Matthew Davies
Abundant Recurrent Mitochondrial Mutations and Widespread Mitonuclear Epistasis in Caenorhabditis elegans
https://www.biorxiv.org/content/10.1101/2025.04.22.650036v1
This cool study analyzes a large collection wild nematodes to find evidence of mitonuclear co-evolution. The authors subsequently used a neat genetic trick to generate different combinations of mitochondrial and nuclear genome and found strong mitonuclear epistasis in many cases.
Picked by: Ethan Ewe
Categories: biochemistry , cancer biology , cell biology , genetics , molecular biology , neuroscience , pharmacology and toxicology
Posted on: 1 May 2025
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Register hereAlso in the biochemistry category:
Keystone Symposium – Metabolic and Nutritional Control of Development and Cell Fate
This preList contains preprints discussed during the Metabolic and Nutritional Control of Development and Cell Fate Keystone Symposia. This conference was organized by Lydia Finley and Ralph J. DeBerardinis and held in the Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States from May 7th to 9th 2024. This meeting marked the first in-person gathering of leading researchers exploring how metabolism influences development, including processes like cell fate, tissue patterning, and organ function, through nutrient availability and metabolic regulation. By integrating modern metabolic tools with genetic and epidemiological insights across model organisms, this event highlighted key mechanisms and identified open questions to advance the emerging field of developmental metabolism.
| List by | Virginia Savy, Martin Estermann |
Biologists @ 100 conference preList
This preList aims to capture all preprints being discussed at the Biologists @100 conference in Liverpool, UK, either as part of the poster sessions or the (flash/short/full-length) talks.
| List by | Reinier Prosee, Jonathan Townson |
February in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry and cell metabolism 2) cell organelles and organisation 3) cell signalling, migration and mechanosensing
| List by | Barbora Knotkova et al. |
Community-driven preList – Immunology
In this community-driven preList, a group of preLighters, with expertise in different areas of immunology have worked together to create this preprint reading list.
| List by | Felipe Del Valle Batalla et al. |
January in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics/gene expression
| List by | Barbora Knotkova et al. |
BSCB-Biochemical Society 2024 Cell Migration meeting
This preList features preprints that were discussed and presented during the BSCB-Biochemical Society 2024 Cell Migration meeting in Birmingham, UK in April 2024. Kindly put together by Sara Morais da Silva, Reviews Editor at Journal of Cell Science.
| List by | Reinier Prosee |
Peer Review in Biomedical Sciences
Communication of scientific knowledge has changed dramatically in recent decades and the public perception of scientific discoveries depends on the peer review process of articles published in scientific journals. Preprints are key vehicles for the dissemination of scientific discoveries, but they are still not properly recognized by the scientific community since peer review is very limited. On the other hand, peer review is very heterogeneous and a fundamental aspect to improve it is to train young scientists on how to think critically and how to evaluate scientific knowledge in a professional way. Thus, this course aims to: i) train students on how to perform peer review of scientific manuscripts in a professional manner; ii) develop students' critical thinking; iii) contribute to the appreciation of preprints as important vehicles for the dissemination of scientific knowledge without restrictions; iv) contribute to the development of students' curricula, as their opinions will be published and indexed on the preLights platform. The evaluations will be based on qualitative analyses of the oral presentations of preprints in the field of biomedical sciences deposited in the bioRxiv server, of the critical reports written by the students, as well as of the participation of the students during the preprints discussions.
| List by | Marcus Oliveira et al. |
CellBio 2022 – An ASCB/EMBO Meeting
This preLists features preprints that were discussed and presented during the CellBio 2022 meeting in Washington, DC in December 2022.
| List by | Nadja Hümpfer et al. |
20th “Genetics Workshops in Hungary”, Szeged (25th, September)
In this annual conference, Hungarian geneticists, biochemists and biotechnologists presented their works. Link: http://group.szbk.u-szeged.hu/minikonf/archive/prg2021.pdf
| List by | Nándor Lipták |
Fibroblasts
The advances in fibroblast biology preList explores the recent discoveries and preprints of the fibroblast world. Get ready to immerse yourself with this list created for fibroblasts aficionados and lovers, and beyond. Here, my goal is to include preprints of fibroblast biology, heterogeneity, fate, extracellular matrix, behavior, topography, single-cell atlases, spatial transcriptomics, and their matrix!
| List by | Osvaldo Contreras |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar et al. |
EMBL Seeing is Believing – Imaging the Molecular Processes of Life
Preprints discussed at the 2019 edition of Seeing is Believing, at EMBL Heidelberg from the 9th-12th October 2019
| List by | Dey Lab |
Cellular metabolism
A curated list of preprints related to cellular metabolism at Biorxiv by Pablo Ranea Robles from the Prelights community. Special interest on lipid metabolism, peroxisomes and mitochondria.
| List by | Pablo Ranea Robles |
MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
Also in the cancer biology category:
Keystone Symposium – Metabolic and Nutritional Control of Development and Cell Fate
This preList contains preprints discussed during the Metabolic and Nutritional Control of Development and Cell Fate Keystone Symposia. This conference was organized by Lydia Finley and Ralph J. DeBerardinis and held in the Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States from May 7th to 9th 2024. This meeting marked the first in-person gathering of leading researchers exploring how metabolism influences development, including processes like cell fate, tissue patterning, and organ function, through nutrient availability and metabolic regulation. By integrating modern metabolic tools with genetic and epidemiological insights across model organisms, this event highlighted key mechanisms and identified open questions to advance the emerging field of developmental metabolism.
| List by | Virginia Savy, Martin Estermann |
April in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics
| List by | Vibha SINGH et al. |
March in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) cancer biology 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics and genomics 6) other
| List by | Girish Kale et al. |
Biologists @ 100 conference preList
This preList aims to capture all preprints being discussed at the Biologists @100 conference in Liverpool, UK, either as part of the poster sessions or the (flash/short/full-length) talks.
| List by | Reinier Prosee, Jonathan Townson |
February in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry and cell metabolism 2) cell organelles and organisation 3) cell signalling, migration and mechanosensing
| List by | Barbora Knotkova et al. |
BSCB-Biochemical Society 2024 Cell Migration meeting
This preList features preprints that were discussed and presented during the BSCB-Biochemical Society 2024 Cell Migration meeting in Birmingham, UK in April 2024. Kindly put together by Sara Morais da Silva, Reviews Editor at Journal of Cell Science.
| List by | Reinier Prosee |
CSHL 87th Symposium: Stem Cells
Preprints mentioned by speakers at the #CSHLsymp23
| List by | Alex Eve |
Journal of Cell Science meeting ‘Imaging Cell Dynamics’
This preList highlights the preprints discussed at the JCS meeting 'Imaging Cell Dynamics'. The meeting was held from 14 - 17 May 2023 in Lisbon, Portugal and was organised by Erika Holzbaur, Jennifer Lippincott-Schwartz, Rob Parton and Michael Way.
| List by | Helen Zenner |
CellBio 2022 – An ASCB/EMBO Meeting
This preLists features preprints that were discussed and presented during the CellBio 2022 meeting in Washington, DC in December 2022.
| List by | Nadja Hümpfer et al. |
Fibroblasts
The advances in fibroblast biology preList explores the recent discoveries and preprints of the fibroblast world. Get ready to immerse yourself with this list created for fibroblasts aficionados and lovers, and beyond. Here, my goal is to include preprints of fibroblast biology, heterogeneity, fate, extracellular matrix, behavior, topography, single-cell atlases, spatial transcriptomics, and their matrix!
| List by | Osvaldo Contreras |
Single Cell Biology 2020
A list of preprints mentioned at the Wellcome Genome Campus Single Cell Biology 2020 meeting.
| List by | Alex Eve |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar et al. |
Lung Disease and Regeneration
This preprint list compiles highlights from the field of lung biology.
| List by | Rob Hynds |
Anticancer agents: Discovery and clinical use
Preprints that describe the discovery of anticancer agents and their clinical use. Includes both small molecules and macromolecules like biologics.
| List by | Zhang-He Goh |
Biophysical Society Annual Meeting 2019
Few of the preprints that were discussed in the recent BPS annual meeting at Baltimore, USA
| List by | Joseph Jose Thottacherry |
Also in the cell biology category:
Keystone Symposium – Metabolic and Nutritional Control of Development and Cell Fate
This preList contains preprints discussed during the Metabolic and Nutritional Control of Development and Cell Fate Keystone Symposia. This conference was organized by Lydia Finley and Ralph J. DeBerardinis and held in the Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States from May 7th to 9th 2024. This meeting marked the first in-person gathering of leading researchers exploring how metabolism influences development, including processes like cell fate, tissue patterning, and organ function, through nutrient availability and metabolic regulation. By integrating modern metabolic tools with genetic and epidemiological insights across model organisms, this event highlighted key mechanisms and identified open questions to advance the emerging field of developmental metabolism.
| List by | Virginia Savy, Martin Estermann |
April in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics
| List by | Vibha SINGH et al. |
March in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) cancer biology 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics and genomics 6) other
| List by | Girish Kale et al. |
Biologists @ 100 conference preList
This preList aims to capture all preprints being discussed at the Biologists @100 conference in Liverpool, UK, either as part of the poster sessions or the (flash/short/full-length) talks.
| List by | Reinier Prosee, Jonathan Townson |
February in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry and cell metabolism 2) cell organelles and organisation 3) cell signalling, migration and mechanosensing
| List by | Barbora Knotkova et al. |
Community-driven preList – Immunology
In this community-driven preList, a group of preLighters, with expertise in different areas of immunology have worked together to create this preprint reading list.
| List by | Felipe Del Valle Batalla et al. |
January in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics/gene expression
| List by | Barbora Knotkova et al. |
December in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) cell cycle and division 2) cell migration and cytoskeleton 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics/gene expression
| List by | Matthew Davies et al. |
November in preprints – the CellBio edition
This is the first community-driven preList! A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. Categories include: 1) cancer cell biology 2) cell cycle and division 3) cell migration and cytoskeleton 4) cell organelles and organisation 5) cell signalling and mechanosensing 6) genetics/gene expression
| List by | Felipe Del Valle Batalla et al. |
BSCB-Biochemical Society 2024 Cell Migration meeting
This preList features preprints that were discussed and presented during the BSCB-Biochemical Society 2024 Cell Migration meeting in Birmingham, UK in April 2024. Kindly put together by Sara Morais da Silva, Reviews Editor at Journal of Cell Science.
| List by | Reinier Prosee |
‘In preprints’ from Development 2022-2023
A list of the preprints featured in Development's 'In preprints' articles between 2022-2023
| List by | Alex Eve, Katherine Brown |
preLights peer support – preprints of interest
This is a preprint repository to organise the preprints and preLights covered through the 'preLights peer support' initiative.
| List by | preLights peer support |
The Society for Developmental Biology 82nd Annual Meeting
This preList is made up of the preprints discussed during the Society for Developmental Biology 82nd Annual Meeting that took place in Chicago in July 2023.
| List by | Joyce Yu, Katherine Brown |
CSHL 87th Symposium: Stem Cells
Preprints mentioned by speakers at the #CSHLsymp23
| List by | Alex Eve |
Journal of Cell Science meeting ‘Imaging Cell Dynamics’
This preList highlights the preprints discussed at the JCS meeting 'Imaging Cell Dynamics'. The meeting was held from 14 - 17 May 2023 in Lisbon, Portugal and was organised by Erika Holzbaur, Jennifer Lippincott-Schwartz, Rob Parton and Michael Way.
| List by | Helen Zenner |
9th International Symposium on the Biology of Vertebrate Sex Determination
This preList contains preprints discussed during the 9th International Symposium on the Biology of Vertebrate Sex Determination. This conference was held in Kona, Hawaii from April 17th to 21st 2023.
| List by | Martin Estermann |
Alumni picks – preLights 5th Birthday
This preList contains preprints that were picked and highlighted by preLights Alumni - an initiative that was set up to mark preLights 5th birthday. More entries will follow throughout February and March 2023.
| List by | Sergio Menchero et al. |
CellBio 2022 – An ASCB/EMBO Meeting
This preLists features preprints that were discussed and presented during the CellBio 2022 meeting in Washington, DC in December 2022.
| List by | Nadja Hümpfer et al. |
Fibroblasts
The advances in fibroblast biology preList explores the recent discoveries and preprints of the fibroblast world. Get ready to immerse yourself with this list created for fibroblasts aficionados and lovers, and beyond. Here, my goal is to include preprints of fibroblast biology, heterogeneity, fate, extracellular matrix, behavior, topography, single-cell atlases, spatial transcriptomics, and their matrix!
| List by | Osvaldo Contreras |
EMBL Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture (2021)
A list of preprints mentioned at the #EESmorphoG virtual meeting in 2021.
| List by | Alex Eve |
FENS 2020
A collection of preprints presented during the virtual meeting of the Federation of European Neuroscience Societies (FENS) in 2020
| List by | Ana Dorrego-Rivas |
Planar Cell Polarity – PCP
This preList contains preprints about the latest findings on Planar Cell Polarity (PCP) in various model organisms at the molecular, cellular and tissue levels.
| List by | Ana Dorrego-Rivas |
BioMalPar XVI: Biology and Pathology of the Malaria Parasite
[under construction] Preprints presented at the (fully virtual) EMBL BioMalPar XVI, 17-18 May 2020 #emblmalaria
| List by | Dey Lab, Samantha Seah |
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Cell Polarity
Recent research from the field of cell polarity is summarized in this list of preprints. It comprises of studies focusing on various forms of cell polarity ranging from epithelial polarity, planar cell polarity to front-to-rear polarity.
| List by | Yamini Ravichandran |
TAGC 2020
Preprints recently presented at the virtual Allied Genetics Conference, April 22-26, 2020. #TAGC20
| List by | Maiko Kitaoka et al. |
3D Gastruloids
A curated list of preprints related to Gastruloids (in vitro models of early development obtained by 3D aggregation of embryonic cells). Updated until July 2021.
| List by | Paul Gerald L. Sanchez and Stefano Vianello |
ECFG15 – Fungal biology
Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome
| List by | Hiral Shah |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar et al. |
EMBL Seeing is Believing – Imaging the Molecular Processes of Life
Preprints discussed at the 2019 edition of Seeing is Believing, at EMBL Heidelberg from the 9th-12th October 2019
| List by | Dey Lab |
Autophagy
Preprints on autophagy and lysosomal degradation and its role in neurodegeneration and disease. Includes molecular mechanisms, upstream signalling and regulation as well as studies on pharmaceutical interventions to upregulate the process.
| List by | Sandra Malmgren Hill |
Lung Disease and Regeneration
This preprint list compiles highlights from the field of lung biology.
| List by | Rob Hynds |
Cellular metabolism
A curated list of preprints related to cellular metabolism at Biorxiv by Pablo Ranea Robles from the Prelights community. Special interest on lipid metabolism, peroxisomes and mitochondria.
| List by | Pablo Ranea Robles |
BSCB/BSDB Annual Meeting 2019
Preprints presented at the BSCB/BSDB Annual Meeting 2019
| List by | Dey Lab |
MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
ASCB/EMBO Annual Meeting 2018
This list relates to preprints that were discussed at the recent ASCB conference.
| List by | Dey Lab, Amanda Haage |
Also in the genetics category:
Keystone Symposium – Metabolic and Nutritional Control of Development and Cell Fate
This preList contains preprints discussed during the Metabolic and Nutritional Control of Development and Cell Fate Keystone Symposia. This conference was organized by Lydia Finley and Ralph J. DeBerardinis and held in the Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States from May 7th to 9th 2024. This meeting marked the first in-person gathering of leading researchers exploring how metabolism influences development, including processes like cell fate, tissue patterning, and organ function, through nutrient availability and metabolic regulation. By integrating modern metabolic tools with genetic and epidemiological insights across model organisms, this event highlighted key mechanisms and identified open questions to advance the emerging field of developmental metabolism.
| List by | Virginia Savy, Martin Estermann |
April in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics
| List by | Vibha SINGH et al. |
March in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) cancer biology 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics and genomics 6) other
| List by | Girish Kale et al. |
Biologists @ 100 conference preList
This preList aims to capture all preprints being discussed at the Biologists @100 conference in Liverpool, UK, either as part of the poster sessions or the (flash/short/full-length) talks.
| List by | Reinier Prosee, Jonathan Townson |
Early 2025 preprints – the genetics & genomics edition
In this community-driven preList, a group of preLighters, with expertise in different areas of genetics and genomics have worked together to create this preprint reading list. Categories include: 1) bioinformatics 2) epigenetics 3) gene regulation 4) genomics 5) transcriptomics
| List by | Chee Kiang Ewe et al. |
January in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics/gene expression
| List by | Barbora Knotkova et al. |
End-of-year preprints – the genetics & genomics edition
In this community-driven preList, a group of preLighters, with expertise in different areas of genetics and genomics have worked together to create this preprint reading list. Categories include: 1) genomics 2) bioinformatics 3) gene regulation 4) epigenetics
| List by | Chee Kiang Ewe et al. |
BSDB/GenSoc Spring Meeting 2024
A list of preprints highlighted at the British Society for Developmental Biology and Genetics Society joint Spring meeting 2024 at Warwick, UK.
| List by | Joyce Yu, Katherine Brown |
BSCB-Biochemical Society 2024 Cell Migration meeting
This preList features preprints that were discussed and presented during the BSCB-Biochemical Society 2024 Cell Migration meeting in Birmingham, UK in April 2024. Kindly put together by Sara Morais da Silva, Reviews Editor at Journal of Cell Science.
| List by | Reinier Prosee |
9th International Symposium on the Biology of Vertebrate Sex Determination
This preList contains preprints discussed during the 9th International Symposium on the Biology of Vertebrate Sex Determination. This conference was held in Kona, Hawaii from April 17th to 21st 2023.
| List by | Martin Estermann |
Alumni picks – preLights 5th Birthday
This preList contains preprints that were picked and highlighted by preLights Alumni - an initiative that was set up to mark preLights 5th birthday. More entries will follow throughout February and March 2023.
| List by | Sergio Menchero et al. |
Semmelweis Symposium 2022: 40th anniversary of international medical education at Semmelweis University
This preList contains preprints discussed during the 'Semmelweis Symposium 2022' (7-9 November), organised around the 40th anniversary of international medical education at Semmelweis University covering a wide range of topics.
| List by | Nándor Lipták |
20th “Genetics Workshops in Hungary”, Szeged (25th, September)
In this annual conference, Hungarian geneticists, biochemists and biotechnologists presented their works. Link: http://group.szbk.u-szeged.hu/minikonf/archive/prg2021.pdf
| List by | Nándor Lipták |
2nd Conference of the Visegrád Group Society for Developmental Biology
Preprints from the 2nd Conference of the Visegrád Group Society for Developmental Biology (2-5 September, 2021, Szeged, Hungary)
| List by | Nándor Lipták |
EMBL Conference: From functional genomics to systems biology
Preprints presented at the virtual EMBL conference "from functional genomics and systems biology", 16-19 November 2020
| List by | Jesus Victorino |
TAGC 2020
Preprints recently presented at the virtual Allied Genetics Conference, April 22-26, 2020. #TAGC20
| List by | Maiko Kitaoka et al. |
ECFG15 – Fungal biology
Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome
| List by | Hiral Shah |
Autophagy
Preprints on autophagy and lysosomal degradation and its role in neurodegeneration and disease. Includes molecular mechanisms, upstream signalling and regulation as well as studies on pharmaceutical interventions to upregulate the process.
| List by | Sandra Malmgren Hill |
Zebrafish immunology
A compilation of cutting-edge research that uses the zebrafish as a model system to elucidate novel immunological mechanisms in health and disease.
| List by | Shikha Nayar |
Also in the molecular biology category:
Keystone Symposium – Metabolic and Nutritional Control of Development and Cell Fate
This preList contains preprints discussed during the Metabolic and Nutritional Control of Development and Cell Fate Keystone Symposia. This conference was organized by Lydia Finley and Ralph J. DeBerardinis and held in the Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States from May 7th to 9th 2024. This meeting marked the first in-person gathering of leading researchers exploring how metabolism influences development, including processes like cell fate, tissue patterning, and organ function, through nutrient availability and metabolic regulation. By integrating modern metabolic tools with genetic and epidemiological insights across model organisms, this event highlighted key mechanisms and identified open questions to advance the emerging field of developmental metabolism.
| List by | Virginia Savy, Martin Estermann |
April in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics
| List by | Vibha SINGH et al. |
Biologists @ 100 conference preList
This preList aims to capture all preprints being discussed at the Biologists @100 conference in Liverpool, UK, either as part of the poster sessions or the (flash/short/full-length) talks.
| List by | Reinier Prosee, Jonathan Townson |
February in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry and cell metabolism 2) cell organelles and organisation 3) cell signalling, migration and mechanosensing
| List by | Barbora Knotkova et al. |
Community-driven preList – Immunology
In this community-driven preList, a group of preLighters, with expertise in different areas of immunology have worked together to create this preprint reading list.
| List by | Felipe Del Valle Batalla et al. |
January in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics/gene expression
| List by | Barbora Knotkova et al. |
2024 Hypothalamus GRC
This 2024 Hypothalamus GRC (Gordon Research Conference) preList offers an overview of cutting-edge research focused on the hypothalamus, a critical brain region involved in regulating homeostasis, behavior, and neuroendocrine functions. The studies included cover a range of topics, including neural circuits, molecular mechanisms, and the role of the hypothalamus in health and disease. This collection highlights some of the latest advances in understanding hypothalamic function, with potential implications for treating disorders such as obesity, stress, and metabolic diseases.
| List by | Nathalie Krauth |
BSCB-Biochemical Society 2024 Cell Migration meeting
This preList features preprints that were discussed and presented during the BSCB-Biochemical Society 2024 Cell Migration meeting in Birmingham, UK in April 2024. Kindly put together by Sara Morais da Silva, Reviews Editor at Journal of Cell Science.
| List by | Reinier Prosee |
‘In preprints’ from Development 2022-2023
A list of the preprints featured in Development's 'In preprints' articles between 2022-2023
| List by | Alex Eve, Katherine Brown |
CSHL 87th Symposium: Stem Cells
Preprints mentioned by speakers at the #CSHLsymp23
| List by | Alex Eve |
9th International Symposium on the Biology of Vertebrate Sex Determination
This preList contains preprints discussed during the 9th International Symposium on the Biology of Vertebrate Sex Determination. This conference was held in Kona, Hawaii from April 17th to 21st 2023.
| List by | Martin Estermann |
Alumni picks – preLights 5th Birthday
This preList contains preprints that were picked and highlighted by preLights Alumni - an initiative that was set up to mark preLights 5th birthday. More entries will follow throughout February and March 2023.
| List by | Sergio Menchero et al. |
CellBio 2022 – An ASCB/EMBO Meeting
This preLists features preprints that were discussed and presented during the CellBio 2022 meeting in Washington, DC in December 2022.
| List by | Nadja Hümpfer et al. |
EMBL Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture (2021)
A list of preprints mentioned at the #EESmorphoG virtual meeting in 2021.
| List by | Alex Eve |
FENS 2020
A collection of preprints presented during the virtual meeting of the Federation of European Neuroscience Societies (FENS) in 2020
| List by | Ana Dorrego-Rivas |
ECFG15 – Fungal biology
Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome
| List by | Hiral Shah |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar et al. |
Lung Disease and Regeneration
This preprint list compiles highlights from the field of lung biology.
| List by | Rob Hynds |
MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
Also in the neuroscience category:
April in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics
| List by | Vibha SINGH et al. |
Biologists @ 100 conference preList
This preList aims to capture all preprints being discussed at the Biologists @100 conference in Liverpool, UK, either as part of the poster sessions or the (flash/short/full-length) talks.
| List by | Reinier Prosee, Jonathan Townson |
2024 Hypothalamus GRC
This 2024 Hypothalamus GRC (Gordon Research Conference) preList offers an overview of cutting-edge research focused on the hypothalamus, a critical brain region involved in regulating homeostasis, behavior, and neuroendocrine functions. The studies included cover a range of topics, including neural circuits, molecular mechanisms, and the role of the hypothalamus in health and disease. This collection highlights some of the latest advances in understanding hypothalamic function, with potential implications for treating disorders such as obesity, stress, and metabolic diseases.
| List by | Nathalie Krauth |
‘In preprints’ from Development 2022-2023
A list of the preprints featured in Development's 'In preprints' articles between 2022-2023
| List by | Alex Eve, Katherine Brown |
CSHL 87th Symposium: Stem Cells
Preprints mentioned by speakers at the #CSHLsymp23
| List by | Alex Eve |
Journal of Cell Science meeting ‘Imaging Cell Dynamics’
This preList highlights the preprints discussed at the JCS meeting 'Imaging Cell Dynamics'. The meeting was held from 14 - 17 May 2023 in Lisbon, Portugal and was organised by Erika Holzbaur, Jennifer Lippincott-Schwartz, Rob Parton and Michael Way.
| List by | Helen Zenner |
FENS 2020
A collection of preprints presented during the virtual meeting of the Federation of European Neuroscience Societies (FENS) in 2020
| List by | Ana Dorrego-Rivas |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar et al. |
SDB 78th Annual Meeting 2019
A curation of the preprints presented at the SDB meeting in Boston, July 26-30 2019. The preList will be updated throughout the duration of the meeting.
| List by | Alex Eve |
Autophagy
Preprints on autophagy and lysosomal degradation and its role in neurodegeneration and disease. Includes molecular mechanisms, upstream signalling and regulation as well as studies on pharmaceutical interventions to upregulate the process.
| List by | Sandra Malmgren Hill |
Young Embryologist Network Conference 2019
Preprints presented at the Young Embryologist Network 2019 conference, 13 May, The Francis Crick Institute, London
| List by | Alex Eve |
Also in the pharmacology and toxicology category:
April in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics
| List by | Vibha SINGH et al. |
FENS 2020
A collection of preprints presented during the virtual meeting of the Federation of European Neuroscience Societies (FENS) in 2020
| List by | Ana Dorrego-Rivas |
COVID-19 / SARS-CoV-2 preprints
List of important preprints dealing with the ongoing coronavirus outbreak. See http://covidpreprints.com for additional resources and timeline, and https://connect.biorxiv.org/relate/content/181 for full list of bioRxiv and medRxiv preprints on this topic
| List by | Dey Lab, Zhang-He Goh |
1
Drug use in special populations
Any drugs that are being used in special populations: Patients with liver and kidney failure, in paediatrics, in geriatrics, and in pregnant or lactating patients. Includes the discovery of factors that could potentially affect drug use in these special populations.
| List by | Zhang-He Goh |
Toxicology of toxicants, existing therapeutics, and investigational drugs
Preprints that describe the toxicology of environmental pollutants and existing and upcoming drugs. Includes both toxicokinetics and toxicodynamics, as well as technological improvements that will help in the characterisation of this field.
| List by | Zhang-He Goh |
Antimicrobials: Discovery, clinical use, and development of resistance
Preprints that describe the discovery of new antimicrobials and any improvements made regarding their clinical use. Includes preprints that detail the factors affecting antimicrobial selection and the development of antimicrobial resistance.
| List by | Zhang-He Goh |
Anticancer agents: Discovery and clinical use
Preprints that describe the discovery of anticancer agents and their clinical use. Includes both small molecules and macromolecules like biologics.
| List by | Zhang-He Goh |
Advances in Drug Delivery
Advances in formulation technology or targeted delivery methods that describe or develop the distribution of small molecules or large macromolecules to specific parts of the body.
| List by | Zhang-He Goh |
Also in the biochemistry category:
Chronic stress antagonizes formation of Stress Granules
Mohammed JALLOH
Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action
Roberto Amadio
Enzymatic access to the rare ΔUA (1→4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control
Adriani Felix et al.
Also in the cancer biology category:
Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasion
Vibha SINGH
Target cell tension regulates macrophage trogocytosis
Felipe Del Valle Batalla
Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer
Teodora Piskova
Also in the cell biology category:
A conserved differentiation program facilitates inhibitory neuron production in the developing mouse and human cerebellum
Jethro Lundie-Brown
Heart Scar-In-A-Dish: Tissue Culture Platform to Study Myocardial Infarct Healing In Vitro
Theodora Stougiannou
Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasion
Vibha SINGH
Also in the genetics category:
3D mechanical confinement directs muscle stem cell fate and function
Justin Gutkowski
Ectopic head regeneration after nervous system ablation in a sea anemone
Isabella Cisneros
Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits
Jeny Jose
Also in the molecular biology category:
Fibroblast growth factor 21 regulates neuromuscular junction innervation through HDAC4 in denervation-induced skeletal muscle atrophy
Jórdan Sampar
Chronic stress antagonizes formation of Stress Granules
Mohammed JALLOH
Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer’s disease models
Jawdat Sandakly
Also in the neuroscience category:
Synapses drive local mitochondrial ATP synthesis to fuel plasticity
Felipe Del Valle Batalla
Fibroblast growth factor 21 regulates neuromuscular junction innervation through HDAC4 in denervation-induced skeletal muscle atrophy
Jórdan Sampar
Unexpected mechanisms of sex-specific memory vulnerabilities to acute traumatic stress
Jimeng Li
Also in the pharmacology and toxicology category:
Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action
Roberto Amadio
Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation
Manuel Lessi
G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics
Simon Cleary
